Darriet Frédéric, Zaim M., Corbel Vincent. (2008). Laboratory evaluation of cyromazine against insecticide-susceptible and -resistant mosquito larvae. Journal of the American Mosquito Control Association, 24 (1), p. 123-126. ISSN 8756-971X.
Titre du document
Laboratory evaluation of cyromazine against insecticide-susceptible and -resistant mosquito larvae
Journal of the American Mosquito Control Association, 2008,
24 (1), p. 123-126 ISSN 8756-971X
In this study, the. activity of cyromazine was evaluated following WHO standard procedures against susceptible and resistant mosquito strains of Anopheles gamhiae, Culex quinquefasciatus, and Aedes aegypti. The dose for 50% and 90% inhibition of adult emergence (IE50 and IE90) ranged from 0.028 mg/liter to 0.17 mg/liter and from 0.075 mg/liter to 0.42 mg/liter, respectively. The effects of cyromazine were closer to that of chitin synthesis inhibitors rather than that of juvenile hormone analogues, with only 10-20% pupal mortality. The toxicity of cyromazine was not strongly affected by the presence of common resistance mechanism, i.e., Kdr mutation and Ace. 1(R) (resistance ratio from 0.5 to 2.3). The absence of cross resistance with common insecticides (pyrethroids, carbamates, organophosphates) makes cyromazine a potential candidate for disease vector control, especially for the management of insecticide resistance.
