Vuillet Laurie, Kojadinovic M., Zappa S., Jaubert M., Adriano J. M., Fardoux Joël, Hannibal Laure, Pignol D., Verméglio A., Giraud Eric. (2007). Evolution of a bacteriophytochrome from light to redox sensor. Embo Journal, 26 (14), p. 3322-3331. ISSN 0261-4189.
Titre du document
Evolution of a bacteriophytochrome from light to redox sensor
Vuillet Laurie, Kojadinovic M., Zappa S., Jaubert M., Adriano J. M., Fardoux Joël, Hannibal Laure, Pignol D., Verméglio A., Giraud Eric
Source
Embo Journal, 2007,
26 (14), p. 3322-3331 ISSN 0261-4189
Bacteriophytochromes are red/far-red photoreceptors that bacteria use to mediate sensory responses to their light environment. Here, we show that the photosynthetic bacterium Rhodopseudomonas palustris has two distinct types of bacteriophytochrome-related protein (RpBphP4) depending upon the strain considered. The first type binds the chromophore biliverdin and acts as a light-sensitive kinase, thus behaving as a bona fide bacteriophytochrome. However, in most strains, RpBphP4 does not to bind this chromophore. This loss of light sensing is replaced by a redox-sensing ability coupled to kinase activity. Phylogenetic analysis is consistent with an evolutionary scenario, where a bacteriophytochrome ancestor has adapted from light to redox sensing. Both types of RpBphP4 regulate the synthesis of light harvesting (LH2) complexes according to the light or redox conditions, respectively. They modulate the affinity of a transcription factor binding to the promoter regions of LH2 complex genes by controlling its phosphorylation status. This is the first complete description of a bacteriophytochrome signal transduction pathway involving a two-component system.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020]
;
Biotechnologies [084]
