Chandre Fabrice, Manguin Sylvie, Brengues Cécile, Dossou Yovo J., Darriet Frédéric, Diabate A., Carnevale Pierre, Guillet Pierre. (1999). Current distribution of a pyrethroid resistance gene (kdr) in Anopheles gambiae complex from West Africa and further evidence for reproductive isolation of the Mopti form. In :
Coluzzi M. (ed.), Bradley D. (ed.). The malaria challenge : after one hundred years of malariology. Parassitologia, 41 (1-3), p. 319-322. The Malaria Challenge : After One Hundred Years of Malariology, Rome (ITA), 1998/11/16-19. ISSN 0048-2951.
Titre du document
Current distribution of a pyrethroid resistance gene (kdr) in Anopheles gambiae complex from West Africa and further evidence for reproductive isolation of the Mopti form
Année de publication
1999
Auteurs
Chandre Fabrice, Manguin Sylvie, Brengues Cécile, Dossou Yovo J., Darriet Frédéric, Diabate A., Carnevale Pierre, Guillet Pierre
In
Coluzzi M. (ed.), Bradley D. (ed.), The malaria challenge : after one hundred years of malariology
Source
Parassitologia, 1999,
41 (1-3), p. 319-322 ISSN 0048-2951
Colloque
The Malaria Challenge : After One Hundred Years of Malariology, Rome (ITA), 1998/11/16-19
In the field, the kdr mutation, involved in pyrethroid resistance, has been found widely distributed in the Savanna form of Anopheles gambiae s.s., but never in wild populations of the Mopti form or An. arabiensis, even in areas where both occur in sympatry with resistant Savanna populations. Under laboratory conditions, Mopti and Savanna forms were fully able to interbreed and the kdr mutation was sure in the field. The absence of the kdr mutation in the Mopti form and the total lack of Mopti-Savanna heterozygotes in field populations provides further evidence of a pre-copulatory barrier to gene flow between these two forms. Molecular markers, including kdr, are powerful tools for studying population genetics and circulation of resistance genes, and should be used through an integrated approach for a better understanding of the speciation process. (Résumé d'auteur)
Plan de classement
Systématique / Morphologie [052ANOPAL01]
Descripteurs
PALUDISME ; MOUSTIQUE ; STRUCTURE GENETIQUE ; MUTATION ; INSECTICIDE ; RESISTANCE ; GENOTYPE ; SPECIATION ; TECHNIQUE PCR ; ETUDE EXPERIMENTALE ; ETUDE COMPARATIVE ; GENE KDR ; PYRETHROIDE
Description Géographique
AFRIQUE DE L'OUEST ; COTE D'IVOIRE ; BURKINA FASO
Localisation
Fonds IRD [F B010020976] ;
Montpellier (Centre IRD)
Identifiant IRD
fdi:010020976
