Léry Xavier, Fédière Gilles, Taha A., Salah M., Giannotti J. (1997). A new small RNA Virus persistently infecting an established cell line of Galleria mellonella, induced by a heterologous infection. Journal of Invertebrate Pathology, 69 (1), p. 7-13.
Titre du document
A new small RNA Virus persistently infecting an established cell line of Galleria mellonella, induced by a heterologous infection
Année de publication
1997
Type de document
Article
Auteurs
Léry Xavier, Fédière Gilles, Taha A., Salah M., Giannotti J.
Source
Journal of Invertebrate Pathology, 1997,
69 (1), p. 7-13
A persistent infection in a "Galleria mellonella cell line was revealed when infected with a maize stem borer picorna-like virus isolated on Sesamia cretica (MSBV). The new virus, completely different from the MSBV, is designated as G. mellonella cell line virus (GmcIV), induces spectacular cytopathic effects, and is a 29-nm-diameter isometric virus, with single-strand RNA of 2.9 X 10 to the 10th power Da molecular weight with a poly(A) tract. Its capsid is constituted of only two major polypeptides, of 34,500 and 32,500 Da, and no minor bands could be detected. The characteristics of the GmcIV do not permit us to classify it with assurance. Even though it has not yet been identified as a picornavirus, it can be classified in the small RNA virus group of the Picornaviridae. G. mellonella represents a very interesting model, owing to the fact that two different persistent viruses belonging to the same family were isolated in vivo and in vitro, to further the understanding of the general phenomenon of persistency and induction. (Résumé d'auteur)
