Publications des scientifiques de l'IRD

Yaya Issifou, Boyer V., Ehlan P. A., Coulibaly A., Agboyibor M. K., Traore I., Kouame M. J. B., Maiga A. K., Kotchi O. R., Nyasenu Y. T., Maradan G., Rojas-Castro D., Diallo F., Anoma C., Dah T. E., Mensah E., Keita B. D., Spire B., Dagnra C. A., Laurent Christian, CohMSM Study Group. (2021). Heterogeneity in the prevalence of high-risk human papillomavirus infection in human immunodeficiency virus-negative and human immunodeficiency virus-positive men who have sex with men in West Africa. Clinical Infectious Diseases, 73 (12), p. 2184-2192. ISSN 1058-4838.

Titre du document
Heterogeneity in the prevalence of high-risk human papillomavirus infection in human immunodeficiency virus-negative and human immunodeficiency virus-positive men who have sex with men in West Africa
Année de publication
2021
Type de document
Article référencé dans le Web of Science WOS:000743384700005
Auteurs
Yaya Issifou, Boyer V., Ehlan P. A., Coulibaly A., Agboyibor M. K., Traore I., Kouame M. J. B., Maiga A. K., Kotchi O. R., Nyasenu Y. T., Maradan G., Rojas-Castro D., Diallo F., Anoma C., Dah T. E., Mensah E., Keita B. D., Spire B., Dagnra C. A., Laurent Christian, CohMSM Study Group
Source
Clinical Infectious Diseases, 2021, 73 (12), p. 2184-2192 ISSN 1058-4838
Background. Men who have sex with men (MSM) are at high risk of human papillomavirus (HPV) infection. We assessed (i) the prevalence of high-risk HPV (HR-HPV) infection and associated factors, and (ii) the prevalence of vaccine-preventable HPV infections in MSM in Burkina Faso, Cote d'Ivoire, Mali, and Togo. Methods. A cross-sectional study was conducted in 2017-2018 among MSM >= 18 years old followed in community-based clinics. HPV infection was investigated in oral and anal samples using the e-BRID system. Factors associated with HR-HPV infection were identified using multivariate logistic regressions. Results. Among 631 participants, 425 were HIV-negative and 206 HIV-positive. HR-HPV prevalence ranged from 9.2% to 34.8% in the former, and 33.3% to 71.0% in the latter, according to the study country. In multivariate analysis, HIV infection (adjusted odds ratio (aOR) 3.61, 95% confidence interval (CI) 2.48-5.27) and study country (4.73, 2.66-8.43 for Mali; 3.12, 1.68-5.80 for Burkina Faso; 3.51, 1.92-6.42 for Togo) were associated with HR-HPV infection. Other associated factors were low educational level, self-defined homosexual identity, and condomless anal sex. The prevalence of infections which can be prevented with bivalent, quadrivalent, and nonavalent vaccines was 5.9, 27.1, and 34.6% in HIV-negative participants, and 18.9, 43.7, and 54.9% in HIV-positive participants, respectively. Conclusions. HR-HPV prevalence was very heterogeneous between the study countries in both HIV-negative and HIV-positive MSM. Vaccine-preventable HPV infections predominated. Vaccination should be proposed to young MSM to reduce the burden of HPV infection in this vulnerable population and their female partners in West Africa.
Plan de classement
Santé : généralités [050] ; Entomologie médicale / Parasitologie / Virologie [052]
Description Géographique
AFRIQUE DE L'OUEST ; BURKINA FASO ; COTE D'IVOIRE ; MALI ; TOGO
Localisation
Fonds IRD [F B010084223]
Identifiant IRD
fdi:010084223
Contact