%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Yaya, Issifou
%A Boyer, V.
%A Ehlan, P. A.
%A Coulibaly, A.
%A Agboyibor, M. K.
%A Traore, I.
%A Kouame, M. J. B.
%A Maiga, A. K.
%A Kotchi, O. R.
%A Nyasenu, Y. T.
%A Maradan, G.
%A Rojas-Castro, D.
%A Diallo, F.
%A Anoma, C.
%A Dah, T. E.
%A Mensah, E.
%A Keita, B. D.
%A Spire, B.
%A Dagnra, C. A.
%A Laurent, Christian
%A CohMSM Study Group
%T Heterogeneity in the prevalence of high-risk human papillomavirus infection in human immunodeficiency virus-negative and human immunodeficiency virus-positive men who have sex with men in West Africa
%D 2021
%L fdi:010084223
%G ENG
%J Clinical Infectious Diseases
%@ 1058-4838
%K HPV ; HIV ; MSM ; Africa
%K AFRIQUE DE L'OUEST ; BURKINA FASO ; COTE D'IVOIRE ; MALI ; TOGO
%M ISI:000743384700005
%N 12
%P 2184-2192
%R 10.1093/cid/ciab157
%U https://www.documentation.ird.fr/hor/fdi:010084223
%> https://www.documentation.ird.fr/intranet/publi/2022-03/010084223.pdf
%V 73
%W Horizon (IRD)
%X Background. Men who have sex with men (MSM) are at high risk of human papillomavirus (HPV) infection. We assessed (i) the prevalence of high-risk HPV (HR-HPV) infection and associated factors, and (ii) the prevalence of vaccine-preventable HPV infections in MSM in Burkina Faso, Cote d'Ivoire, Mali, and Togo. Methods. A cross-sectional study was conducted in 2017-2018 among MSM >= 18 years old followed in community-based clinics. HPV infection was investigated in oral and anal samples using the e-BRID system. Factors associated with HR-HPV infection were identified using multivariate logistic regressions. Results. Among 631 participants, 425 were HIV-negative and 206 HIV-positive. HR-HPV prevalence ranged from 9.2% to 34.8% in the former, and 33.3% to 71.0% in the latter, according to the study country. In multivariate analysis, HIV infection (adjusted odds ratio (aOR) 3.61, 95% confidence interval (CI) 2.48-5.27) and study country (4.73, 2.66-8.43 for Mali; 3.12, 1.68-5.80 for Burkina Faso; 3.51, 1.92-6.42 for Togo) were associated with HR-HPV infection. Other associated factors were low educational level, self-defined homosexual identity, and condomless anal sex. The prevalence of infections which can be prevented with bivalent, quadrivalent, and nonavalent vaccines was 5.9, 27.1, and 34.6% in HIV-negative participants, and 18.9, 43.7, and 54.9% in HIV-positive participants, respectively. Conclusions. HR-HPV prevalence was very heterogeneous between the study countries in both HIV-negative and HIV-positive MSM. Vaccine-preventable HPV infections predominated. Vaccination should be proposed to young MSM to reduce the burden of HPV infection in this vulnerable population and their female partners in West Africa.
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