Publications des scientifiques de l'IRD

Wichit S., Gumpangseth N., Hamel Rodolphe, Yainoy S., Arikit S., Punsawad C., Missé Dorothée. (2021). Chikungunya and Zika viruses : co-circulation and the interplay between viral proteins and host factors. Pathogens, 10 (4), 448 [27 p.].

Titre du document
Chikungunya and Zika viruses : co-circulation and the interplay between viral proteins and host factors
Année de publication
2021
Type de document
Article référencé dans le Web of Science WOS:000643349200001
Auteurs
Wichit S., Gumpangseth N., Hamel Rodolphe, Yainoy S., Arikit S., Punsawad C., Missé Dorothée
Source
Pathogens, 2021, 10 (4), 448 [27 p.]
Chikungunya and Zika viruses, both transmitted by mosquito vectors, have globally re-emerged over for the last 60 years and resulted in crucial social and economic concerns. Presently, there is no specific antiviral agent or vaccine against these debilitating viruses. Understanding viral-host interactions is needed to develop targeted therapeutics. However, there is presently limited information in this area. In this review, we start with the updated virology and replication cycle of each virus. Transmission by similar mosquito vectors, frequent co-circulation, and occurrence of co-infection are summarized. Finally, the targeted host proteins/factors used by the viruses are discussed. There is an urgent need to better understand the virus-host interactions that will facilitate antiviral drug development and thus reduce the global burden of infections caused by arboviruses.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020] ; Entomologie médicale / Parasitologie / Virologie [052]
Description Géographique
HAITI ; COLOMBIE ; BRESIL ; NICARAGUA ; EQUATEUR ; MEXIQUE
Localisation
Fonds IRD [F B010081379]
Identifiant IRD
fdi:010081379
Contact