@article{fdi:010081379,
  title = {{C}hikungunya and {Z}ika viruses : co-circulation and the interplay between viral proteins and host factors},
  author = {{W}ichit, {S}. and {G}umpangseth, {N}. and {H}amel, {R}odolphe and {Y}ainoy, {S}. and {A}rikit, {S}. and {P}unsawad, {C}. and {M}iss{\'e}, {D}oroth{\'e}e},
  editor = {},
  language = {{ENG}},
  abstract = {{C}hikungunya and {Z}ika viruses, both transmitted by mosquito vectors, have globally re-emerged over for the last 60 years and resulted in crucial social and economic concerns. {P}resently, there is no specific antiviral agent or vaccine against these debilitating viruses. {U}nderstanding viral-host interactions is needed to develop targeted therapeutics. {H}owever, there is presently limited information in this area. {I}n this review, we start with the updated virology and replication cycle of each virus. {T}ransmission by similar mosquito vectors, frequent co-circulation, and occurrence of co-infection are summarized. {F}inally, the targeted host proteins/factors used by the viruses are discussed. {T}here is an urgent need to better understand the virus-host interactions that will facilitate antiviral drug development and thus reduce the global burden of infections caused by arboviruses.},
  keywords = {{C}hikungunya virus ; {Z}ika virus ; antiviral ; arbovirus ; arbovirus-host ; interactions ; {HAITI} ; {COLOMBIE} ; {BRESIL} ; {NICARAGUA} ; {EQUATEUR} ; {MEXIQUE}},
  booktitle = {},
  journal = {{P}athogens},
  volume = {10},
  numero = {4},
  pages = {448 [27 ]},
  year = {2021},
  DOI = {10.3390/pathogens10040448},
  URL = {https://www.documentation.ird.fr/hor/fdi:010081379},
}