Publications des scientifiques de l'IRD

Sanhueza D., Chevillon C., Colwell R., Babonneau J., Marion E., Marsollier L., Guégan Jean-François. (2016). Chitin promotes Mycobacterium ulcerans growth. FEMS Microbiology Ecology, 92, art. no fiw067 [6 p.]. ISSN 0168-6496.

Titre du document
Chitin promotes Mycobacterium ulcerans growth
Année de publication
2016
Type de document
Article référencé dans le Web of Science WOS:000377473600002
Auteurs
Sanhueza D., Chevillon C., Colwell R., Babonneau J., Marion E., Marsollier L., Guégan Jean-François
Source
FEMS Microbiology Ecology, 2016, 92, art. no fiw067 [6 p.] ISSN 0168-6496
Equally contributed as co-supervisors of this work One sentence summary: Chitin increased Mycobacterium Ulcerans (MU) growth significantly providing a nutrient source or environmental support for the bacillus, thereby, providing a focus on the association between MU and aquatic arthropods. ABSTRACT Mycobacterium ulcerans (MU) is the causative agent of Buruli ulcer, an emerging human infectious disease. However, both the ecology and life cycle of MU are poorly understood. The occurrence of MU has been linked to the aquatic environment, notably water bodies affected by human activities. It has been hypothesized that one or a combination of environmental factor(s) connected to human activities could favour growth of MU in aquatic systems. Here, we tested in vitro the growth effect of two ubiquitous polysaccharides and five chemical components on MU at concentration ranges shown to occur in endemic regions. Real-time PCR showed that chitin increased MU growth significantly providing a nutrient source or environmental support for the bacillus, thereby, providing a focus on the association between MU and aquatic arthropods. Aquatic environments with elevated population of arthropods provide increased chitin availability and, thereby, enhanced multiplication of MU. If calcium very slightly enhanced MU growth, iron, zinc, sulphate and phosphate did not stimulate MU growth, and at the concentration ranges of this study would limit MU population in natural ecosystems.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020] ; Entomologie médicale / Parasitologie / Virologie [052]
Localisation
Fonds IRD [F B010067158]
Identifiant IRD
fdi:010067158
Contact