@article{fdi:010067158,
  title = {{C}hitin promotes {M}ycobacterium ulcerans growth},
  author = {{S}anhueza, {D}. and {C}hevillon, {C}. and {C}olwell, {R}. and {B}abonneau, {J}. and {M}arion, {E}. and {M}arsollier, {L}. and {G}u{\'e}gan, {J}ean-{F}ran{\c{c}}ois},
  editor = {},
  language = {{ENG}},
  abstract = {{E}qually contributed as co-supervisors of this work {O}ne sentence summary: {C}hitin increased {M}ycobacterium {U}lcerans ({MU}) growth significantly providing a nutrient source or environmental support for the bacillus, thereby, providing a focus on the association between {MU} and aquatic arthropods. {ABSTRACT} {M}ycobacterium ulcerans ({MU}) is the causative agent of {B}uruli ulcer, an emerging human infectious disease. {H}owever, both the ecology and life cycle of {MU} are poorly understood. {T}he occurrence of {MU} has been linked to the aquatic environment, notably water bodies affected by human activities. {I}t has been hypothesized that one or a combination of environmental factor(s) connected to human activities could favour growth of {MU} in aquatic systems. {H}ere, we tested in vitro the growth effect of two ubiquitous polysaccharides and five chemical components on {MU} at concentration ranges shown to occur in endemic regions. {R}eal-time {PCR} showed that chitin increased {MU} growth significantly providing a nutrient source or environmental support for the bacillus, thereby, providing a focus on the association between {MU} and aquatic arthropods. {A}quatic environments with elevated population of arthropods provide increased chitin availability and, thereby, enhanced multiplication of {MU}. {I}f calcium very slightly enhanced {MU} growth, iron, zinc, sulphate and phosphate did not stimulate {MU} growth, and at the concentration ranges of this study would limit {MU} population in natural ecosystems.},
  keywords = {{ZONE} {TROPICALE}},
  booktitle = {},
  journal = {{FEMS} {M}icrobiology {E}cology},
  volume = {92},
  numero = {},
  pages = {art. no fiw067 [6 ]},
  ISSN = {0168-6496},
  year = {2016},
  DOI = {10.1093/femsec/fiw067},
  URL = {https://www.documentation.ird.fr/hor/fdi:010067158},
}