Chesnais Cédric, Missamou F., Pion Sébastien, Bopda J., Louya F., Majewski A. C., Weil G. J., Boussinesq Michel. (2013). Short report : semi-quantitative scoring of an immunochromatographic test for circulating filarial antigen. American Journal of Tropical Medicine and Hygiene, 89 (5), p. 916-918. ISSN 0002-9637.
Titre du document
Short report : semi-quantitative scoring of an immunochromatographic test for circulating filarial antigen
Chesnais Cédric, Missamou F., Pion Sébastien, Bopda J., Louya F., Majewski A. C., Weil G. J., Boussinesq Michel
Source
American Journal of Tropical Medicine and Hygiene, 2013,
89 (5), p. 916-918 ISSN 0002-9637
The value of a semi-quantitative scoring of the filarial antigen test (Binax Now Filariasis card test, ICT) results was evaluated during a field survey in. the Republic of Congo. One hundred and thirty-four (134) of 774 tests (17.3%) were clearly positive and were scored 1, 2, or 3; and 11 (1.4%) had questionable results. Wuchereria bancrofti microfilariae (mf) were detected in 41 of those 133 individuals with an ICT test score 1 who also had a night blood smear; none of the 11 individuals with questionable ICT results harbored night mf. Cuzick's test showed a significant trend for higher microfilarial densities in groups with higher ICT scores (P < 0.001). The ICT scores were also significantly correlated with blood mf counts. Because filarial antigen levels provide an indication of adult worm infection intensity, our results suggest that semi-quantitative reading of the ICT may be useful for grading the intensity of filarial infections in individuals and populations.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020]
;
Entomologie médicale / Parasitologie / Virologie [052]
