%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Chesnais, Cédric
%A Missamou, F.
%A Pion, Sébastien
%A Bopda, J.
%A Louya, F.
%A Majewski, A. C.
%A Weil, G. J.
%A Boussinesq, Michel
%T Short report : semi-quantitative scoring of an immunochromatographic test for circulating filarial antigen
%D 2013
%L fdi:010061346
%G ENG
%J American Journal of Tropical Medicine and Hygiene
%@ 0002-9637
%K CONGO
%M ISI:000326904100015
%N 5
%P 916-918
%R 10.4269/ajtmh.13-0245
%U https://www.documentation.ird.fr/hor/fdi:010061346
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-08/010061346.pdf
%V 89
%W Horizon (IRD)
%X The value of a semi-quantitative scoring of the filarial antigen test (Binax Now Filariasis card test, ICT) results was evaluated during a field survey in. the Republic of Congo. One hundred and thirty-four (134) of 774 tests (17.3%) were clearly positive and were scored 1, 2, or 3; and 11 (1.4%) had questionable results. Wuchereria bancrofti microfilariae (mf) were detected in 41 of those 133 individuals with an ICT test score 1 who also had a night blood smear; none of the 11 individuals with questionable ICT results harbored night mf. Cuzick's test showed a significant trend for higher microfilarial densities in groups with higher ICT scores (P < 0.001). The ICT scores were also significantly correlated with blood mf counts. Because filarial antigen levels provide an indication of adult worm infection intensity, our results suggest that semi-quantitative reading of the ICT may be useful for grading the intensity of filarial infections in individuals and populations.
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