Three new potent cytotoxic macrolides closely related to sphinxolide from the New Caledonia sponge #Neosiphonia superstes$

Three new potent cytotoxic macrolides closely related to sphinxolide from the New Caledonia sponge #Neosiphonia superstes$ D'Auria V. auteur aut IRD Paloma L.G. auteur aut IRD Minale L. auteur aut IRD Zampella A. auteur aut IRD Verbist J.F. auteur aut IRD Roussakis C. auteur aut IRD Debitus Cécile auteur aut IRD text journalArticle eng text/pdf reformatted digital access Three new macrolides 2-4 have been isolated with sphinxolide 1 from the marine sponge N. superstes collected off New Caledonia. The structures of the new compounds were determined by interpretation of NMR spectral data as well as comparison of spectral data with those of 1. These compounds were highly cytotoxic against various human carcinoma cells. (Résumé d'auteur) specialized INVERTEBRE AQUATIQUE SUBSTANCE NATURELLE STRUCTURE CHIMIQUE ACTIVITE BIOLOGIQUE EPONGE MACROLIDE SPHINXOLIDE CYTOTOXICITE ACTIVITE ANTI TUMORALE NOUVELLE CALEDONIE 035SUBSAN02 Tetrahedron 49 38 8657-8664 1993 0040-4020 https://www.documentation.ird.fr/hor/fdi:39874 10.1016/S0040-4020(01)96271-4 0040-4020 [F B39874] https://www.documentation.ird.fr/hor/fdi:39874 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/pleins_textes_6/b_fdi_35-36/39874.pdf IRD - Base Horizon / Pleins textes 1994-08-05 2015-07-02 fdi:39874 fre