%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture non répertoriées par l'AERES %A D'Auria, V. %A Paloma, L.G. %A Minale, L. %A Zampella, A. %A Verbist, J.F. %A Roussakis, C. %A Debitus, Cécile %T Three new potent cytotoxic macrolides closely related to sphinxolide from the New Caledonia sponge Neosiphonia superstes %D 1993 %L fdi:39874 %G ENG %J Tetrahedron %@ 0040-4020 %K INVERTEBRE AQUATIQUE ; SUBSTANCE NATURELLE ; STRUCTURE CHIMIQUE ; ACTIVITE BIOLOGIQUE %K EPONGE ; MACROLIDE ; SPHINXOLIDE ; CYTOTOXICITE ; ACTIVITE ANTI TUMORALE %K NOUVELLE CALEDONIE %N 38 %P 8657-8664 %R 10.1016/S0040-4020(01)96271-4 %U https://www.documentation.ird.fr/hor/fdi:39874 %> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/pleins_textes_6/b_fdi_35-36/39874.pdf %V 49 %W Horizon (IRD) %X Three new macrolides 2-4 have been isolated with sphinxolide 1 from the marine sponge #N. superstes$ collected off New Caledonia. The structures of the new compounds were determined by interpretation of NMR spectral data as well as comparison of spectral data with those of 1. These compounds were highly cytotoxic against various human carcinoma cells. (Résumé d'auteur) %$ 035SUBSAN02