Three new potent cytotoxic macrolides closely related to sphinxolide from the New Caledonia sponge Neosiphonia superstes D'Auria, V. Paloma, L.G. Minale, L. Zampella, A. Verbist, J.F. Roussakis, C. /Debitus, Cécile INVERTEBRE AQUATIQUE SUBSTANCE NATURELLE STRUCTURE CHIMIQUE ACTIVITE BIOLOGIQUE EPONGE MACROLIDE SPHINXOLIDE CYTOTOXICITE ACTIVITE ANTI TUMORALE Three new macrolides 2-4 have been isolated with sphinxolide 1 from the marine sponge N. superstes collected off New Caledonia. The structures of the new compounds were determined by interpretation of NMR spectral data as well as comparison of spectral data with those of 1. These compounds were highly cytotoxic against various human carcinoma cells. (Résumé d'auteur) 1993 text https://www.documentation.ird.fr/hor/fdi:39874 fdi:39874 D'Auria V., Paloma L.G., Minale L., Zampella A., Verbist J.F., Roussakis C., Debitus Cécile. Three new potent cytotoxic macrolides closely related to sphinxolide from the New Caledonia sponge Neosiphonia superstes. 1993, 49 (38), 8657-8664 EN NOUVELLE CALEDONIE