@article{fdi:39874, title = {{T}hree new potent cytotoxic macrolides closely related to sphinxolide from the {N}ew {C}aledonia sponge {N}eosiphonia superstes}, author = {{D}'{A}uria, {V}. and {P}aloma, {L}.{G}. and {M}inale, {L}. and {Z}ampella, {A}. and {V}erbist, {J}.{F}. and {R}oussakis, {C}. and {D}ebitus, {C}{\'e}cile}, editor = {}, language = {{ENG}}, abstract = {{T}hree new macrolides 2-4 have been isolated with sphinxolide 1 from the marine sponge #{N}. superstes$ collected off {N}ew {C}aledonia. {T}he structures of the new compounds were determined by interpretation of {NMR} spectral data as well as comparison of spectral data with those of 1. {T}hese compounds were highly cytotoxic against various human carcinoma cells. ({R}{\'e}sum{\'e} d'auteur)}, keywords = {{INVERTEBRE} {AQUATIQUE} ; {SUBSTANCE} {NATURELLE} ; {STRUCTURE} {CHIMIQUE} ; {ACTIVITE} {BIOLOGIQUE} ; {EPONGE} ; {MACROLIDE} ; {SPHINXOLIDE} ; {CYTOTOXICITE} ; {ACTIVITE} {ANTI} {TUMORALE} ; {NOUVELLE} {CALEDONIE}}, booktitle = {}, journal = {{T}etrahedron}, volume = {49}, numero = {38}, pages = {8657--8664}, ISSN = {0040-4020}, year = {1993}, DOI = {10.1016/{S}0040-4020(01)96271-4}, URL = {https://www.documentation.ird.fr/hor/fdi:39874}, }