Metabolites of the new Caledonian sponge Cladocroce incurvata Valeria d'Auria, M. Gomez Paloma, L. Minale, L. Riccio, R. Zampella, A. /Debitus, Cécile SUBSTANCE NATURELLE INVERTEBRE AQUATIQUE STRUCTURE CHIMIQUE ANALYSE SPECTRALE EPONGE MOLECULE METABOLITE CLADOCROCINE ACIDE CLADOCROIQUE The deep-water New Caledonian sponge Cladocroce incurvata contains two "polyketide" metabolites. Cladocrocin A (1) appears to be derived from fatty acid with ethyl side chains, thus incorporating butyrate units. Cladocroic acid (2) is a straight chain fatty acid which incorporates a terminal enyne functionality and a cycloproprane ring directly attached to the carboxylic acid function. The structures were elucidated by interpretation of spectral data, and the cis stereochemistry of the cyclopropane ring in cladocroic acid (2) was derived after the synthesis of cis - and trans - 2, 3 - methanohexanoic acid models and nmr spectral comparisons. (Résumé d'auteur) 1993 text https://www.documentation.ird.fr/hor/fdi:39871 fdi:39871 Valeria d'Auria M., Gomez Paloma L., Minale L., Riccio R., Zampella A., Debitus Cécile. Metabolites of the new Caledonian sponge Cladocroce incurvata. 1993, 56 (3), 418-423 EN NOUVELLE CALEDONIE