@article{fdi:24433,
  title = {{M}alaria, cause of ahaptoglobinaemia in {A}fricans},
  author = {{T}rape, {J}ean-{F}ran{\c{c}}ois and {F}ribourg-{B}lanc, {A}. and {B}osseno, {M}arie-{F}rance and {L}allemant, {M}arc and {E}ngler, {R}. and {M}ouchet, {J}ean},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he lack of serum haptoglobin in {A}fricans has been investigated in the {C}ongo, {C}entral {A}frica, where {H}p{O} prevalence is about 30%. {T}his study shows that it is possible to suppress ahaptoglobinaemia within a few weeks by antimalarial chemoprophylaxis, that it does not occur in protected individuals, that ahaptoglobinaemia reappears at its original incidence levels after interruption of chemoprophylaxis, and that some individuals are more susceptible in relation to {H}p2 gene. {M}alaria is the only significant cause of ahaptoglobinaemia in subjects both with and without detectable parasitaemia. {T}he possible mechanisms involved are discussed.},
  keywords = {{ENFANT} {D}'{AGE} {SCOLAIRE} ; {PALUDISME} ; {CHIMIOPROPHYLAXIE} ; {MALADIES} {ASSOCIEES} ; {AHAPTOGLOBINEMIE} ; {AMODIAQUINE} ; {MEFLOQUINE} ; {CONGO} ; {BRAZZAVILLE} {REGION} ; {LINZOLO}},
  booktitle = {},
  journal = {{T}ransactions of the {R}oyal {S}ociety of {T}ropical {M}edicine and {H}ygiene},
  volume = {79},
  numero = {},
  pages = {430--434},
  ISSN = {0035-9203},
  year = {1985},
  DOI = {10.1016/0035-9203(85)90053-7},
  URL = {https://www.documentation.ird.fr/hor/fdi:24433},
}