@article{fdi:010097025, title = {{B}ioactive polysaccharides from {D}jiboutian brown algae : antioxidant and anti-aging potential for cosmetic applications}, author = {{N}our, {M}. and {P}etek, {S}ylvain and {D}aher, {A}. and {C}{\'e}rantola, {S}. and {C}osquer, {N}. and {D}eslandes, {E}. and {S}tiger-{P}ouvreau, {V}.}, editor = {}, language = {{ENG}}, abstract = {{B}rown macroalgae are a valuable source of bioactive polysaccharides, particularly alginates and fucoidans, with significant potential for cosmetic and pharmaceutical applications. {I}n this study, polysaccharides were extracted from four species ({P}adina pavonica, {S}argassum ilicifolium, {S}. latifolium, and {T}urbinaria decurrens) collected along the {D}jibouti coastline. {S}tructural characterization by {FT}-{IR} and 1{H}-{NMR} revealed pronounced interspecific variability. {A}lginates displayed distinct mannuronate/guluronate ({M}/{G}) ratios, with {S}argassum latifolium showing the highest and {T}. decurrens the lowest, reflecting differences in polymer composition and structural flexibility. {F}ucoidan spectra exhibited characteristic sulfate bands at 1217-1220 and 840 cm-1, with lower transmission values for {T}. decurrens indicating a relatively higher degree of sulfation. {B}iological assays demonstrated that alginate extracts exhibited moderate antioxidant activity, whereas fucoidans showed significantly stronger radical scavenging ({DPPH}) and ferric reducing ({FRAP}) capacities, in some cases comparable to vitamin {C}. {F}ucoidans also displayed potent inhibition of skin-aging enzymes, with elastase inhibition reaching 62.1% for {P}. pavonica and tyrosinase inhibition peaking at 63% for {S}. ilicifolium at 0.5 mg/m{L}. {T}hese results highlight the critical role of structural features, particularly sulfation patterns, in determining biological activity. {O}verall, {D}jiboutian brown algal polysaccharides combine antioxidant and enzyme inhibitory properties, confirming their potential as multifunctional and sustainable marine-derived ingredients for cosmetic formulations.}, keywords = {brown algae ; fucoidans ; alginates ; antioxidant activity ; anti-aging ; enzymes ; {DJIBOUTI} ; {TADJOURAH} {GOLFE}}, booktitle = {}, journal = {{C}osmetics}, volume = {13}, numero = {2}, pages = {53 [19 p.]}, year = {2026}, DOI = {10.3390/cosmetics13020053}, URL = {https://www.documentation.ird.fr/hor/fdi:010097025}, }