@article{fdi:010096703,
  title = {{T}icks as vectors of {T}rypanosomatidae with medical or veterinary interest : insights and implications from a comprehensive systematic review and meta-analysis},
  author = {{K}ernif, {T}. and {M}edrouh, {B}. and {E}ddaikra, {N}. and {O}ury, {B}runo and {H}olzmuller, {P}. and {S}ereno, {D}enis},
  editor = {},
  language = {{ENG}},
  abstract = {{S}ince the 20th century, numerous studies have detected or isolated parasites from the {T}rypanosomatidae family in various tick species. {H}owever, the status of ticks as vectors for medically or

veterinary significant {T}rypanosoma and {L}eishmania remains unclear. {W}e conducted a systematic review and meta-analysis to provide new insights into the potential vector status of these path-

ogens, which have significant medical and veterinary implications. {W}e searched three databases ({P}ub{M}ed, {G}oogle {S}cholar, and {W}eb of {S}cience) from 1912 to {J}une 30, 2023, resulting in 94

papers included in the qualitative analysis and 86 papers in the quantitative analysis. {A}ll identified field studies were conducted in endemic areas and investigated the presence of {T}rypanosoma

and {L}eishmania parasites, {DNA}, or antigens in ticks. {W}e recorded a pooled prevalence of {T}rypanosomatidae detection in ticks at 15.48 % [7.99-24.61 %], with significant variations depending

on the year, detection method, and geographical area. {M}ost of the infected tick species belonged to the genera {A}mblyomma, {H}yalomma, {I}xodes, and {R}hipicephalus. {E}xperimental laboratory work on

transmission routes demonstrated potential vector competence in both the {A}rgasidae and {I}xodidae tick families. {A}lthough our systematic review and meta-analysis provide compelling evidence

of the natural infection of ticks by {T}rypanosomatidae parasites, along with some evidence of non-traditional transmission routes, they do not offer conclusive evidence regarding the role of ticks as

biological or mechanical vectors for {T}rypanosomatidae species of veterinary and medical interest. {T}his highlights the urgent need for additional investigations to address this point.},
  keywords = {},
  booktitle = {},
  journal = {{H}eliyon},
  volume = {10},
  numero = {24},
  pages = {e40895 [31 ]},
  ISSN = {2405-8440},
  year = {2024},
  DOI = {10.1016/j.heliyon.2024.e40895},
  URL = {https://www.documentation.ird.fr/hor/fdi:010096703},
}