@article{fdi:010096421,
  title = {{T}he effect of increased temperature on dengue virus in the vector {A}edes aegypti from {N}ew {C}aledonia},
  author = {{D}elrieu, {M}. and {O}'{C}onnor, {O}. and {P}ocquet, {N}. and {T}eraiharoa, {K}. and {G}riffon, {A}. {F}. and {M}enk{\`e}s, {C}hristophe and {M}angeas, {M}organ and {V}iennet, {E}. and {B}urtet-{S}arramegna, {V}. and {D}upont-{R}ouzeyrol, {M}. and {F}rentiu, {F}. {D}.},
  editor = {},
  language = {{ENG}},
  abstract = {{D}engue virus ({DENV}) is a major public health concern in tropical and subtropical regions, including the {P}acific. {T}emperature is recognised as a major driver of transmission under climate change. {U}nderstanding how higher temperatures may alter {DENV} transmission is essential to anticipate future dengue risk. {T}herefore, we assessed the effect of temperature on {DENV}-1 in {A}edes aegypti from {N}ew {C}aledonia. {M}osquitoes were orally infected and maintained for 14 days at 26.6 degrees {C} (average temperatures during recent outbreaks) or 31.1 degrees {C} ({SSP}5-8.5 scenario projected temperatures). {M}osquito bodies, heads, and saliva were analysed separately to determine infection, dissemination, and transmission rates as well as transmission efficiencies. {I}nfectious virus was detected by using a fluorescent focus assay, and viral titres were quantified via {TCID}50 assays. {N}o significant differences were observed in infection, dissemination, and transmission rates or transmission efficiencies between the two temperatures. {H}owever, {DENV} titres in mosquito bodies and heads were significantly higher at 31.1 degrees {C} than 26.6 degrees {C}. {O}ur results indicate that elevated temperature increases viral loads within the insect but not the proportion of infectious mosquitoes, highlighting the importance of considering temperature as a key parameter in assessing dengue risk under climate change. {F}urther studies are needed to investigate the effects of temperature on virus-mosquito interactions.},
  keywords = {temperature ; climate change ; dengue virus ; {A}edes aegypti ; viral replication ; {NOUVELLE} {CALEDONIE}},
  booktitle = {},
  journal = {{T}ropical {M}edicine and {I}nfectious {D}isease},
  volume = {11},
  numero = {2},
  pages = {53 [9 p.]},
  ISSN = {2414-6366},
  year = {2026},
  DOI = {10.3390/tropicalmed11020053},
  URL = {https://www.documentation.ird.fr/hor/fdi:010096421},
}