@article{fdi:010095371,
  title = {{M}alaria epidemiology in the {K}orhogo area, {N}orthern {C}{\^o}te d'{I}voire : baseline assessment prior to a randomized controlled trial},
  author = {{T}chiekoi, {N}. {B}. and {Z}ogo, {M}. {B}. and {A}lou, {L}. {P}. {A}. and {S}om{\'e}, {A}. and {S}oma, {D}. {D}. and {C}oulibaly, {I}. and {K}on{\'e}, {A}. and {F}ournet, {F}lorence and {T}aconet, {P}aul and {D}ahounto, {A}. and {B}aba-{M}oussa, {L}. and {D}abir{\'e}, {R}. {K}. and {M}oiroux, {N}icolas and {K}offi, {A}. {A}. and {P}ennetier, {C}{\'e}dric and {A}ssi, {S}. {B}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {W}idespread {I}nsecticide resistance among malaria vector populations poses a significant threat to the efficacy of current vector control strategies. {T}his highlights the urgent need for innovative approaches that integrate existing tools with those under development. {T}he primary objective of this study was to characterize the malaria epidemiological profile in the {K}orhogo region prior to the implementation of complementary vector control tools alongside long-lasting insecticidal nets ({LLIN}s). {B}oth passive and active case detection methods were employed. {M}ethods {P}assive case detection involved data collection from heath care facilities between {J}uly 2016 and {J}uly 2017, covering a total of 398,424 person-weeks from 26 villages in the {K}orhogo health district, northern {C} & ocirc;te d'{I}voire. {A}ctive case detection was carried out through three cross-sectional surveys ({CSS}) conducted in {S}eptember 2016, {D}ecember 2016 and {M}arch 2017. {D}uring these surveys, individuals under 21 years of age were invited to attend clinical consultations. {T}hose presenting with fever (> 37,5 degrees {C}) were tested for malaria with rapid diagnostic test ({RDT}), and individuals with a positive result were treated with artemisinin-based combination therapy ({ACT}). {A}ctive case detection during the surveys enabled the estimation of malaria case prevalence, defined as the proportion of population with symptoms and a positive {RDT} at the time of the survey. {A}dditionally, in a randomly selected sub-sample of six villages, thick blood smears were analysed-regardless of symptoms-to assess the prevalence of malaria infection in the general population during {CSS}. {R}esults {T}he mean weekly malaria incidence throughout the year in the overall population was 0.25 cases per 100 person-weeks, corresponding to 130 cases per 1000 person-years. {D}uring {CSS}, malaria cases prevalence ranged from 13.4% during the dry season to 43.4% in the late rainy season. {T}he highest malaria cases' prevalence was observed in children under 5 years of age, with significant decline in older age groups. {T}hick blood smears from six villages revealed parasite prevalence between 85.4% and 100%. {P}lasmodium falciparum accounted for 97% of single infection, although mixed infections with {P}lasmodium malariae and {P}lasmodium ovale were also detected. {C}onclusion {A}ctive case detection conducted through three transversal surveys indicates that the study area exhibits characteristics of malaria transmission hotspot. {T}he region's dense hydrographic network provides a favourable ecological and epidemiological context for assessing additional vector control strategies to supplement universal {LLIN}s coverage in the fight against malaria.},
  keywords = {{M}alaria ; {P}revalence ; {V}ector control ; {K}orhogo ; {C}{\^o}te d'{I}voire ; {COTE} {D}'{IVOIRE}},
  booktitle = {},
  journal = {{M}alaria {J}ournal},
  volume = {24},
  numero = {1},
  pages = {309 [13 p.]},
  year = {2025},
  DOI = {10.1186/s12936-025-05571-8},
  URL = {https://www.documentation.ird.fr/hor/fdi:010095371},
}