@article{fdi:010095313, title = {{A}ssessment of seroprevalence of {M}pox virus infection among sex workers in {C}hiang {M}ai, {T}hailand}, author = {{U}mer, {M}. and {C}hawansuntati, {K}. and {W}ipasa, {J}. and {J}indaphun, {K}. and {K}otemul, {K}. and {T}hant, {Y}. {M}. and {N}go-{G}iang-{H}uong, {N}icole and {K}hamduang, {W}. and {H}ongjaisee, {S}.}, editor = {}, language = {{ENG}}, abstract = {{O}bjectives: {T}he 2022 global {M}pox outbreak revealed major surveillance gaps, particularly among marginalized populations such as sex workers, whose role in undetected {MPXV} transmission remains poorly understood. {T}his study aims to assess the seroprevalence of {MPXV} {I}g{G} antibodies and identify associated risk factors among sex workers in {C}hiang {M}ai, {T}hailand. {M}ethods: {I}n this cross-sectional study, 262 sex workers recruited from {M}arch to {D}ecember 2022 were tested for prior {MPXV} exposure using an in-house indirect {ELISA} targeting the recombinant {MPXV} {E}8{L} antigen. {L}ogistic regression models were used to identify demographic and behavioral factors associated with seropositivity. {R}esults: {MPXV} {I}g{G} seroprevalence was 4.6% (12/262). {S}eropositivity was significantly higher among males than females (5.2% vs 4.0%, {P} = 0.011). {I}n multivariable analysis, male gender ({OR} = 3.23, 95% {CI}: 1.109.47, {P} = 0.032), blood transfusion history ({OR} = 4.40, 95% {CI}: 1.35-14.25, {P} = 0.013) and sharing sharp objects with others ({OR} = 4.55, 95% {CI}: 1.12-18.48, {P} = 0.034) were significantly associated with {M}pox seropositivity. {C}onclusion: {O}ur findings reveal undetected {MPXV} circulation among {C}hiang {M}ai sex workers. {T}he identified risk factors suggest overlapping parenteral and sexual vulnerabilities, emphasizing the need for integrated surveillance and targeted interventions.}, keywords = {{M}pox virus ; {S}eroprevalence ; {S}ex workers ; {I}n-house {ELISA} ; {E}8{L} antigen ; {T}hailand ; {THAILANDE} ; {CHIANG} {MAI}}, booktitle = {}, journal = {{I}nternational {J}ournal of {I}nfectious {D}iseases}, volume = {160}, numero = {}, pages = {108041 [9 p.]}, ISSN = {1201-9712}, year = {2025}, DOI = {10.1016/j.ijid.2025.108041}, URL = {https://www.documentation.ird.fr/hor/fdi:010095313}, }