@article{fdi:010095305, title = {{M}aternal anthropometric measurements in pregnancy and child neurocognitive and behavioral development at 1 and 6 years of age: {A} cohort study in {B}enin, {S}ub-{S}aharan {A}frica}, author = {{K}erri, {A}. and {H}eude, {B}. and {Z}oumenou, {R}. and {B}oivin, {M}. {J}. and {C}ot, {M}ichel and {M}assougbodji, {A}. and {B}odeau-{L}ivinec, {F}.}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {L}ow and high body mass index ({BMI}) are hypothesized to impact offspring neurodevelopment, but less is known in sub-{S}aharan {A}frica where undernutrition is highly prevalent. {O}bjective: {T}he aim of this study was to investigate the association between maternal anthropometric measurements during pregnancy and neurocognitive and behavioral development in children at age 1 and 6 years, in a mother-child cohort from {B}enin. {M}ethods: {T}his prospective cohort study included surviving singletons born to pregnant women in {A}llada, {B}enin. {C}ognitive and motor functions of 747 and 574 children were assessed at 1 and 6 years of age, respectively, in addition to behavioral difficulties and attention deficit and hyperactivity disorders. {S}tatistical analysis using multiple linear regression models tested main associations, potential mediating factors were additionally adjusted for. {R}esults: {T}otal of 17%, 72.5%, 7.7% and 2.5% of women were estimated to be underweight, normal weight, overweight and obese before pregnancy, respectively. {W}omen who were underweight had a higher median weight gain (240 [170-300]) over the course of pregnancy, compared to normal {BMI} women (210 [160-260]), and overweight/obese women (150 [110-240]). {A}fter exclusion of obese women, estimated prepregnancy {BMI} was significantly associated with higher motor scores (0.26, 95% {CI} 0.002-0.53) and cognitive scores (0.37, 95% {CI} 0.02-0.72) after adjustment for confounding factors. {T}here was no association between gestational weight gain and offspring neurodevelopment at 1 and 6 years of age. {T}here was no association between maternal {BMI} and gestational weight gain and behavior and attention deficit and hyperactivity disorders at 6 years of age. {C}onclusions: {O}ur study suggests that low {BMI} before pregnancy may impair short- and long-term neurocognition in children in the {B}eninese context. {U}ndernutrition in childhood has great impact and efforts to adequate prevention for both child and maternal undernutrition should be enforced in low- and middle-income countries.}, keywords = {{P}regnancy ; {C}ognition ; {B}ody mass index ; {T}hinness ; {G}estational weight gain ; {C}hild development ; {M}alnutrition ; {BENIN} ; {AFRIQUE} {SUBSAHARIENNE}}, booktitle = {}, journal = {{N}utrition}, volume = {141}, numero = {}, pages = {112914 [5 ]}, ISSN = {0899-9007}, year = {2026}, DOI = {10.1016/j.nut.2025.112914}, URL = {https://www.documentation.ird.fr/hor/fdi:010095305}, }