@article{fdi:010094972,
  title = {{M}ale sterility in {D}rosophila mojavensis x {D}. arizonae hybrids is not caused by gene movements in the {Y} chromosome},
  author = {{V}anderlinde, {T}. and {U}no, {F}. and {G}oldstein, {G}. and {S}abot, {F}ran{\c{c}}ois and {C}arareto, {C}. {M}. {A}. and {V}ieira, {C}. and {M}arkow, {T}. {A}. and {C}arvalho, {A}. {B}.},
  editor = {},
  language = {{ENG}},
  abstract = {{Y} chromosomes play important roles in sex determination, male fertility, and, in some cases, hybrid male sterility. {N}early 40 years ago, {Z}ouros and co-workers found that {D}rosophila mojavensis males carrying a {Y} chromosome from the sibling species {D}. arizonae are sterile, with fertility restored by chromosome 4 from {D}. arizonae. {W}hile these findings could result from gene interactions, they may also suggest the movement of an essential male fertility gene from the {Y} to chromosome 4 in the {D}. arizonae lineage. {T}o test this, we analyzed the {Y}-linked gene content of {D}. mojavensis, {D}. arizonae, and the closely related {D}. navojoa. {W}e identified 5 previously unreported {Y}-linked genes, bringing the total to 14. {T}hese genes fit the pattern observed in other {D}rosophila species: they originated from autosomal, testis-specific genes that duplicated onto the {Y} chromosome. {A}ll {Y}-linked genes are shared between {D}. arizonae and {D}. mojavensis, ruling out the movement of a protein-coding gene as the cause of sterility. {H}owever, we found a huge difference in the copy number of {GI}26128, an {HP}1 gene family member, with similar to 1,400 {Y}-linked copies in {D}. arizonae but only 6 in {D}. mojavensis, making it a candidate to explain the hybrid male sterility.},
  keywords = {mojavensis cluster ; {Y} chromosome ; gene duplication ; hybrid sterility ; {D}rosophila},
  booktitle = {},
  journal = {{E}volution},
  volume = {{E}arly access},
  numero = {},
  pages = {[13 p.]},
  ISSN = {0014-3820},
  year = {2025},
  DOI = {10.1093/evolut/qpaf163},
  URL = {https://www.documentation.ird.fr/hor/fdi:010094972},
}