@article{fdi:010094809, title = {{S}quirrel reservoirs of monkeypox virus are sister species separated by the {S}anaga {R}iver ({C}ameroon), as are the two main viral clades}, author = {{C}uraudeau, {M}. and {P}eterhans, {J}. {K}. and {L}e {F}lanchec, {T}. and {G}ilissen, {E}. and {G}ranjon, {L}aurent and {B}arale, {L}. and {G}essain, {A}. and {H}assanin, {A}.}, editor = {}, language = {{ENG}}, abstract = {{M}onkeypox is an emerging infectious disease of unclear zoonotic origin in {A}frica although increasing evidence suggests that rope squirrels are reservoirs of the monkeypox virus ({MPXV}). {H}ere, we describe new data on the systematics of rope squirrels ({S}ciuridae, {F}unisciurus). {O}ur molecular phylogeny strongly supports the polyphyly of {F}unisciurus pyrropus, with a {C}entral {A}frican clade sister to {F}unisciurus leucogenys and a {W}est {A}frican clade sister to {F}unisciurus anerythrus. {M}useum specimens show that the two clades have distinct pelage patterns. {W}e propose therefore to resurrect the name {F}unisciurus leucostigma for the {W}est {A}frican clade. {U}sing reliable taxonomic identifications of georeferenced squirrels, we inferred the ecological niches of the three species of interest. {T}he {S}anaga {R}iver in {C}ameroon appears to be the barrier separating both the sister species {F}. anerythrus and {F}. leucostigma as well as the sister {MPXV} clades {I} and {II}. {T}his suggests that these two {MPXV} clades were isolated in {C}entral and {W}est {A}frica, respectively, due to allopatric squirrel speciation.}, keywords = {{M}onkeypox virus ; {R}eservoir host ; {O}ne health ; {A}nimal systematics ; {F}unisciurus ; {C}oevolution ; {P}hylogeography ; {G}eographic barrier ; {CAMEROUN} ; {SANAGA} {COURS} {D}'{EAU}}, booktitle = {}, journal = {{O}ne {H}ealth}, volume = {21}, numero = {}, pages = {101157 [9 p.]}, year = {2025}, DOI = {10.1016/j.onehlt.2025.101157}, URL = {https://www.documentation.ird.fr/hor/fdi:010094809}, }