@article{fdi:010094152, title = {{T}he effect of sexual and gender minority violence on depression, hazardous drinking, condom use, and {HIV} acquisition : an individual participant data meta-analysis of the {C}oh{MSM}, {HPTN} 075, and {A}nza {M}apema {C}ohort {S}tudies in {A}frica}, author = {{S}tannah, {J}. and {K}night, {J}. and {S}andfort, {T}. and {L}aurent, {C}hristian and {O}tieno, {F}. {O}. and {L}armarange, {J}oseph and {C}oulaud, {P}. {J}. and {M}udhune, {V}. and {H}amilton, {E}. and {C}ummings, {V}. and {S}pire, {B}. and {R}eynolds, {D}. and {D}adabhai, {S}. and {O}kall, {D}. and {K}eita, {B}. {D}. and {S}agaon {T}eyssier, {L}uis and {P}anchia, {R}. and {B}oily, {M}. {C}. and {M}aheu-{G}iroux, {M}.}, editor = {}, language = {{ENG}}, abstract = {{S}ome sexual and gender minorities ({SGM}), including men who have sex with men and transgender women, are disproportionately vulnerable to {HIV}. {M}any {SGM} in {A}frica report experiencing verbal or physical violence due to their sexual and/or gender identities or behaviours. {T}he pathways linking such {SGM} violence to {HIV} acquisition are complex. {W}e described experiences of verbal and physical {SGM} violence and explored pathways to {HIV} acquisition among {SGM} assigned male sex at birth using a two-stage individual participant data meta-analysis of three {A}frican cohort studies: {C}oh{MSM} ({B}urkina {F}aso, {C}{\^o}te d'{I}voire, {M}ali, {T}ogo), {HPTN} 075 ({K}enya, {M}alawi, {S}outh {A}frica), and {A}nza {M}apema ({K}enya). {SGM} violence was assessed at baseline and follow-up visits. {W}e fit log-linear sequential conditional mean models using generalised estimating equations to estimate risk ratios linking {SGM} violence, moderate-to-severe depressive symptoms, hazardous drinking, condom use, and {HIV} acquisition, adjusted for baseline confounders and previous exposure and outcome. {W}e pooled study estimates using random effects meta-analysis. {SGM} violence, mostly verbal, was reported by 36% (570/1590) participants at baseline (past 6-12 months), and 20% (321/1590) during the first year of follow-up (past 3-6 months). {B}aseline {SGM} violence was not associated with {HIV} acquisition (pooled adjusted risk ratio [a{RR}] = 1.0, 95% {CI} 0.5-1.9). {D}uring follow-up, {SGM} violence also showed no clear relationship with {HIV}, but was linked to depressive symptoms at the same visit (pooled a{RR} = 1.7, 1.3-2.1), in turn associated with hazardous drinking (pooled a{RR} = 1.4, 1.1-1.7). {I}mpacts on condom use were inconclusive. {SGM} in {A}frica face high rates of violence, which are associated with depressive symptoms and hazardous drinking-potential routes to {HIV} vulnerability. {W}hile our study did not conclusively demonstrate higher {HIV} incidence among {SGM} reporting violence, interventions to reduce violence and support mental health remain crucial.}, keywords = {{S}tructural determinants ; {S}exual and gender minorities ; {H}omophobic violence ; {HIV} incidence ; {I}ndividual participant data meta-analysis ; {M}ental health ; {BURKINA} {FASO} ; {COTE} {D}'{IVOIRE} ; {MALI} ; {TOGO} ; {KENYA} ; {MALAWI} ; {AFRIQUE} {DU} {SUD} ; {KENYA}}, booktitle = {}, journal = {{A}ids and {B}ehavior}, volume = {[{E}arly acces]}, numero = {}, pages = {[16 ]}, ISSN = {1090-7165}, year = {2025}, DOI = {10.1007/s10461-025-04799-4}, URL = {https://www.documentation.ird.fr/hor/fdi:010094152}, }