%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Cooper, L.V.
%A Robson, A.
%A Trotter, C.L.
%A Aseffa, A.
%A Collard, J.M.
%A Daugla, D.M.
%A Diallo, A.
%A Hodgson, A.
%A Jusot, J.F.
%A Omotara, B.
%A Sow, S.
%A Hassan-King, M.
%A Manigart, O.
%A Nascimento, M.
%A Woukeu, A.
%A Chandramohan, D.
%A Borrow, R.
%A Maiden, M.C.J.
%A Greenwood, B.
%A Stuart, J.M.
%A Trape, Jean-François
%A et al.
%T Risk factors for acquisition of meningococcal carriage in the African meningitis belt
%D 2019
%L fdi:010093839
%G ENG
%J Tropical Medicine and International Health
%@ 1360-2276
%M ISI:000463036800002
%N 4
%P 392-400
%R 10.1111/tmi.13203
%U https://www.documentation.ird.fr/hor/fdi:010093839
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2025-07/010093839.pdf
%V 24
%W Horizon (IRD)
%X Objective: To investigate potential risk factors for acquisition in seven countries of the meningitis belt. Methods: Households were followed up every 2 weeks for 2 months, then monthly for a further 4 months. Pharyngeal swabs were collected from all available household members at each visit and questionnaires completed. Risks of acquisition over the whole study period and for each visit were analysed by a series of logistic regressions. Results: Over the course of the study, acquisition was higher in: (i) 5-to 14-year olds, as compared with those 30 years or older (OR 3.6, 95% CI 1.4-9.9); (ii) smokers (OR 3.6, 95% CI 0.98-13); and (iii) those exposed to wood smoke at home (OR 2.6 95% CI 1.3-5.6). The risk of acquisition from one visit to the next was higher in those reporting a sore throat during the dry season (OR 3.7, 95% CI 2.0-6.7) and lower in those reporting antibiotic use (OR 0.17, 95% CI 0.03-0.56). Conclusions: Acquisition of meningococcal carriage peaked in school age children. Recent symptoms of sore throat during the dry season, but not during the rainy season, were associated with a higher risk of acquisition. Upper respiratory tract infections may be an important driver of epidemics in the meningitis belt.
%$ 050MEDECI