<?xml version="1.0"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Risk factors for acquisition of meningococcal carriage in the African meningitis belt</dc:title>
  <dc:creator>Cooper, L.V.</dc:creator>
  <dc:creator>Robson, A.</dc:creator>
  <dc:creator>Trotter, C.L.</dc:creator>
  <dc:creator>Aseffa, A.</dc:creator>
  <dc:creator>Collard, J.M.</dc:creator>
  <dc:creator>Daugla, D.M.</dc:creator>
  <dc:creator>Diallo, A.</dc:creator>
  <dc:creator>Hodgson, A.</dc:creator>
  <dc:creator>Jusot, J.F.</dc:creator>
  <dc:creator>Omotara, B.</dc:creator>
  <dc:creator>Sow, S.</dc:creator>
  <dc:creator>Hassan-King, M.</dc:creator>
  <dc:creator>Manigart, O.</dc:creator>
  <dc:creator>Nascimento, M.</dc:creator>
  <dc:creator>Woukeu, A.</dc:creator>
  <dc:creator>Chandramohan, D.</dc:creator>
  <dc:creator>Borrow, R.</dc:creator>
  <dc:creator>Maiden, M.C.J.</dc:creator>
  <dc:creator>Greenwood, B.</dc:creator>
  <dc:creator>Stuart, J.M.</dc:creator>
  <dc:creator>/Trape, Jean-Fran&#xE7;ois</dc:creator>
  <dc:creator>et al.</dc:creator>
  <dc:description>Objective: To investigate potential risk factors for acquisition in seven countries of the meningitis belt. Methods: Households were followed up every 2 weeks for 2 months, then monthly for a further 4 months. Pharyngeal swabs were collected from all available household members at each visit and questionnaires completed. Risks of acquisition over the whole study period and for each visit were analysed by a series of logistic regressions. Results: Over the course of the study, acquisition was higher in: (i) 5-to 14-year olds, as compared with those 30 years or older (OR 3.6, 95% CI 1.4-9.9); (ii) smokers (OR 3.6, 95% CI 0.98-13); and (iii) those exposed to wood smoke at home (OR 2.6 95% CI 1.3-5.6). The risk of acquisition from one visit to the next was higher in those reporting a sore throat during the dry season (OR 3.7, 95% CI 2.0-6.7) and lower in those reporting antibiotic use (OR 0.17, 95% CI 0.03-0.56). Conclusions: Acquisition of meningococcal carriage peaked in school age children. Recent symptoms of sore throat during the dry season, but not during the rainy season, were associated with a higher risk of acquisition. Upper respiratory tract infections may be an important driver of epidemics in the meningitis belt.</dc:description>
  <dc:date>2019</dc:date>
  <dc:type>text</dc:type>
  <dc:identifier>https://www.documentation.ird.fr/hor/fdi:010093839</dc:identifier>
  <dc:identifier>fdi:010093839</dc:identifier>
  <dc:identifier>Cooper L.V., Robson A., Trotter C.L., Aseffa A., Collard J.M., Daugla D.M., Diallo A., Hodgson A., Jusot J.F., Omotara B., Sow S., Hassan-King M., Manigart O., Nascimento M., Woukeu A., Chandramohan D., Borrow R., Maiden M.C.J., Greenwood B., Stuart J.M., Trape Jean-Fran&#xE7;ois, et al.. Risk factors for acquisition of meningococcal carriage in the African meningitis belt. 2019, 24 (4), 392-400</dc:identifier>
  <dc:language>EN</dc:language>
</oai_dc:dc>
