@article{fdi:010093839, title = {{R}isk factors for acquisition of meningococcal carriage in the {A}frican meningitis belt}, author = {{C}ooper, {L}.{V}. and {R}obson, {A}. and {T}rotter, {C}.{L}. and {A}seffa, {A}. and {C}ollard, {J}.{M}. and {D}augla, {D}.{M}. and {D}iallo, {A}. and {H}odgson, {A}. and {J}usot, {J}.{F}. and {O}motara, {B}. and {S}ow, {S}. and {H}assan-{K}ing, {M}. and {M}anigart, {O}. and {N}ascimento, {M}. and {W}oukeu, {A}. and {C}handramohan, {D}. and {B}orrow, {R}. and {M}aiden, {M}.{C}.{J}. and {G}reenwood, {B}. and {S}tuart, {J}.{M}. and {T}rape, {J}ean-{F}ran{\c{c}}ois and et al.}, editor = {}, language = {{ENG}}, abstract = {{O}bjective: {T}o investigate potential risk factors for acquisition in seven countries of the meningitis belt. {M}ethods: {H}ouseholds were followed up every 2 weeks for 2 months, then monthly for a further 4 months. {P}haryngeal swabs were collected from all available household members at each visit and questionnaires completed. {R}isks of acquisition over the whole study period and for each visit were analysed by a series of logistic regressions. {R}esults: {O}ver the course of the study, acquisition was higher in: (i) 5-to 14-year olds, as compared with those 30 years or older ({OR} 3.6, 95% {CI} 1.4-9.9); (ii) smokers ({OR} 3.6, 95% {CI} 0.98-13); and (iii) those exposed to wood smoke at home ({OR} 2.6 95% {CI} 1.3-5.6). {T}he risk of acquisition from one visit to the next was higher in those reporting a sore throat during the dry season ({OR} 3.7, 95% {CI} 2.0-6.7) and lower in those reporting antibiotic use ({OR} 0.17, 95% {CI} 0.03-0.56). {C}onclusions: {A}cquisition of meningococcal carriage peaked in school age children. {R}ecent symptoms of sore throat during the dry season, but not during the rainy season, were associated with a higher risk of acquisition. {U}pper respiratory tract infections may be an important driver of epidemics in the meningitis belt.}, keywords = {}, booktitle = {}, journal = {{T}ropical {M}edicine and {I}nternational {H}ealth}, volume = {24}, numero = {4}, pages = {392--400}, ISSN = {1360-2276}, year = {2019}, DOI = {10.1111/tmi.13203}, URL = {https://www.documentation.ird.fr/hor/fdi:010093839}, }