@article{fdi:010093837,
  title = {{M}alaria determinants among adults of {D}ielmo, a {S}enegal malaria endemic village, before the introduction of long lasting insecticide treated bed-nets : an 18 years longitudinal study},
  author = {{W}otodjo, {A}.{N}. and {D}oucoure, {S}. and {D}iagne, {N}afissatou and {T}all, {A}. and {T}rape, {J}ean-{F}ran{\c{c}}ois and {S}okhna, {C}heikh},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground : {L}ittle data on malaria morbidity among {A}frican adults exposed since birth to intense malaria transmission are available. {T}his study aimed to investigate malaria morbidity determinants among adults living in {D}ielmo village, {S}enegal, where a longitudinal epidemiological study was carried out over an 18-year period before the introduction of insecticide treated nets. {M}ethods : {B}etween {J}uly 1990 and {J}une 2008, a longitudinal study was carried out in {D}ielmo, a {S}enegalese village, among adults aged at least 15 years to evaluate determinants of {P}. falciparum clinical malaria attacks. {M}alaria diagnosis was confirmed by thick blood smear. {D}ata were analyzed using a random-effect negative binomial regression. {R}esults : {O}f a total of 12,253 person-trimester observations, 768 {P}. falciparum uncomplicated clinical malaria attacks, and a series of biological and epidemiological parameters were analyzed. {T}o be aged 30 years or more, combination therapy treatment period, and being born in the village of {D}ielmo were significantly associated with a lower risk of clinical malaria; while the third trimester of the year (rainy season) and pregnancy were significantly associated with an increased risk of clinical malaria. {N}one of the biological parameters investigated were associated with the occurrence of malaria attacks. {C}onclusion : {T}his study provides longitudinal data on malaria among adults exposed to intense perennial transmission. {I}t shows that the incidence of the disease among adults decreased first rapidly then progressively with age during the different treatment policies periods, with pregnancy as only individual major factor of increased risk of clinical malaria among those investigated in our study.},
  keywords = {{SENEGAL} ; {DIELMO}},
  booktitle = {},
  journal = {{A}frican {J}ournal of {P}araistology, {M}ycology and {E}ntomology},
  volume = {2},
  numero = {1},
  pages = {10 [14 ]},
  ISSN = {1987-1473},
  year = {2024},
  URL = {https://www.documentation.ird.fr/hor/fdi:010093837},
}