@article{fdi:010093525,
  title = {{R}ice {JASMONIC} {ACID} {OXIDASES} control resting jasmonate metabolism to promote growth and repress basal immune responses},
  author = {{N}decky, {S}. and {M}alherbe, {L}. and {V}illette, {C}. and {C}halvon, {V}. and {M}eusnier, {I}. and {B}eltran-{V}alencia, {D}. and {B}aumberger, {N}. and {R}iemann, {M}. and {K}roj, {T}. and {C}hampion, {A}ntony and {H}eitz, {T}.},
  editor = {},
  language = {{ENG}},
  abstract = {{C}atabolic conversions within the jasmonate pathway have substantial consequences on phytohormone signaling output. {I}n dicots, the jasmonic acid oxidase ({JAO}) catabolic route leads to jasmonic acid ({JA}) hydroxylation, which limits its conjugation into bioactive jasmonoyl-isoleucine ({JA}-{I}le). {H}ere, we functionally characterized the {JAO} pathway in rice ({O}ryza sativa) and demonstrated its key function in promoting growth and attenuating {JA} responses in vegetative tissues. {T}he rice genome encodes 4 {JAO}-related homologs, 3 of which generate hydroxy-{JA} in vitro and rescue the high-defense phenotype of the {A}rabidopsis jao2-2 mutant. {B}y generating and analyzing a series of single to quadruple rice jao mutants, we showed additive effects of cumulative {JAO} depletion on {JA} metabolism, basal defense levels, growth inhibition, fitness, and global metabolic reprogramming. {T}he growth of {JAO}-deficient lines was substantially repressed at the juvenile stage, while the impact was milder in later vegetative development, during which plants opposed enhanced resistance to virulent and avirulent strains of {M}agnaporthe oryzae, the causal agent of fungal blast disease. {M}oreover, jao mutants exhibited slightly reduced fertility and impaired seed filling. {O}ur findings identify the {JAO} pathway as an integral component of basal {JA}/{JA}-{I}le homeostasis and an important determinant of the growth-defense tradeoff in rice. {T}he regulatory function of this pathway is conserved in monocots, opening possibilities for selectively modulating basal {JA} responses in major cereal crops to optimize agronomic traits. {T}he jasmonic acid oxidase pathway shapes resting jasmonic acid homeostasis and impacts the growth-defense tradeoff in rice.},
  keywords = {},
  booktitle = {},
  journal = {{P}lant {P}hysiology},
  volume = {198},
  numero = {1},
  pages = {kiaf161 [19 ]},
  ISSN = {0032-0889},
  year = {2025},
  DOI = {10.1093/plphys/kiaf161},
  URL = {https://www.documentation.ird.fr/hor/fdi:010093525},
}