@article{fdi:010093378,
  title = {{D}eterminants of {SARS}-{C}o{V}-2 infection across three sentinels sites in {B}enin during 2021 : a multicentric surveillance study},
  author = {{A}tchade, {A}. and {Y}adouleton, {A}. and {F}iogbe, {M}. and {A}lfa, {D}. {A}. and {Y}ovo, {E}. and {L}e {H}esran, {J}ean-{Y}ves and {H}ounsa, {S}. and {B}ationo, {C}{\'e}dric and {F}igueroa-{R}omero, {A}. and {G}audart, {J}. and {G}onzalez, {R}. and {B}onnet, {E}mmanuel and {M}assougbodji, {A}. and {C}ottrell, {G}illes},
  editor = {},
  language = {{ENG}},
  abstract = {{I}n the context of the {COVID}-19 pandemic, {B}enin, like other regions in sub-{S}aharan {A}frica and around the world, has been grappling with a public health crisis since march 2020. {T}he country responded to this crisis by implementing adaptive response measures. {T}he {STREESCO} project is part of this dynamic effort, strengthening epidemiological surveillance at three sentinel sites. {T}his study thoroughly examines the determinants of {SARS}-{C}o{V}-2 infection. {T}his involved strategic support based in {C}otonou, {A}llada, and {N}atitingou. {D}ata collection took place from march 1 to november 30, with individuals voluntarily undergoing {COVID}-19 screening at dedicated health units. {B}efore participation, free and informed consent was obtained. {T}he collected data included sociodemographic information, clinical details, and the results of {COVID}-19 tests. {A} multivariate logistic regression model was used to identify factors associated with {SARS}-{C}o{V}-2 infection. {S}urveillance included 4178 participants, with a male/female ratio of 0.98 and a median age of 33 ({IQR}: 25-45). {A}cross all sites, 13.12% of participants tested positive for {SARS}-{C}o{V}-2, and 85.40% of them had a {SARS}-{C}o{V}-2 infection.of participants were symptomatic at baseline. {T}he proportion of positivity was 6%, 11% and 28% respectively during phases 1, 2 and 3 of the national strategy. {I}dentified risk factors included the {A}llada site (a{OR} 2.04, 95%{CI} 1.59-2.62), phase 3 (a{OR} 3.16, 95%{CI} 2.34-4.27), phase 2 (a{OR} 1.67, 95%{CI} 1.12-2.51), secondary (a{OR} 1.67, 95%{CI} 1.12-2.51) and higher level of education (a{OR} 1.83, 95%{CI} 1.22-2.74), respiratory symptoms (a{OR} 1.88, 95%{CI} 1.40-2.53), and/or anosmia/ageusia (a{OR} 1.88, 95%{CI} 1.48-2.38). {C}onversely, the {N}atitingou site (a{OR} = 0.29, 95%{CI}: 0.20-0.42), group living (a{OR} = 0.75, 95%{CI}: 0.60-0.94), and digestive symptoms (a{OR} = 0.70, 95%{CI}: 0.54-0.91) were associated with a reduced risk of infection. {T}hese results underscore the importance of active surveillance during crisis situations, ensuring the acquisition of reliable and persuasive data to enhance individual care and guide health policies.{T}rial registration {NCT}06170320 (retrospectively registered on {D}ecember 21, 2023).},
  keywords = {{BENIN} ; {AFRIQUE} {SUBSAHARIENNE} ; {COTONOU}},
  booktitle = {},
  journal = {{PL}o{S} {G}lobal {P}ublic {H}ealth},
  volume = {5},
  numero = {2},
  pages = {e0004227 [18 p.]},
  year = {2025},
  DOI = {10.1371/journal.pgph.0004227},
  URL = {https://www.documentation.ird.fr/hor/fdi:010093378},
}