@article{fdi:010093231,
  title = {{A}ssociation of close-range contact patterns with {SARS}-{C}o{V}-2 : a household transmission study},
  author = {{K}leynhans, {J}. and {D}all'{A}mico, {L}. and {G}auvin, {L}a{\¨e}titia and {T}izzoni, {M}. and {M}aloma, {L}. and {W}alaza, {S}. and {M}artinson, {N}.{A}. and von {G}ottberg, {A}. and {W}olter, {N}. and {M}akhasi, {M}. and {C}ohen, {C}. and {C}attuto, {C}. and {T}empia, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {H}ouseholds are an important location for severe acute respiratory syndrome coronavirus 2 ({SARS}-{C}o{V}-2) transmission, especially during periods when travel and work was restricted to essential services. {W}e aimed to assess the association of close-range contact patterns with {SARS}-{C}o{V}-2 transmission. {M}ethods: {W}e deployed proximity sensors for two weeks to measure face-to-face interactions between household members after {SARS}-{C}o{V}-2 was identified in the household, in {S}outh {A}frica, 2020-2021. {W}e calculated the duration, frequency, and average duration of close-range proximity events with {SARS}-{C}o{V}-2 index cases. {W}e assessed the association of contact parameters with {SARS}-{C}o{V}-2 transmission using mixed effects logistic regression accounting for index and household member characteristics. {R}esults: {W}e included 340 individuals (88 {SARS}-{C}o{V}-2 index cases and 252 household members). {O}n multivariable analysis, factors associated with {SARS}-{C}o{V}-2 acquisition were index cases with minimum {C}t value <30 (a{OR} 16.8 95% {CI} 3.1-93.1) vs >35, and female contacts (a{OR} 2.5 95% {CI} 1.3-5.0). {N}o contact parameters were associated with acquisition (a{OR} 1.0-1.1) for any of the duration, frequency, cumulative time in contact, or average duration parameters. {C}onclusions: {W}e did not find an association between close-range proximity events and {SARS}-{C}o{V}-2 household transmission. {O}ur findings may be due to study limitations, that droplet-mediated transmission during close-proximity contacts plays a smaller role than airborne transmission of {SARS}-{C}o{V}-2 in the household, or due to high contact rates in households.},
  keywords = {{AFRIQUE} {DU} {SUD} ; {KLERKSDORP} ; {SOWETO}},
  booktitle = {},
  journal = {e{L}ife},
  volume = {12},
  numero = {},
  pages = {e84753 [26 ]},
  ISSN = {2050-084{X}},
  year = {2023},
  DOI = {10.7554/elife.84753},
  URL = {https://www.documentation.ird.fr/hor/fdi:010093231},
}