@article{fdi:010092921,
  title = {{T}eosinte {P}ollen {D}rive guides maize diversification and domestication by {RNA}i},
  author = {{B}erube, {B}. and {E}rnst, {E}. and {C}ahn, {J}. and {R}oche, {B}enjamin and de {S}antis {A}lves, {C}. and {L}ynn, {J}. and {S}cheben, {A}. and {G}rimanelli, {D}aniel and {S}iepel, {A}. and {R}oss-{I}barra, {J}. and {K}ermicle, {J}. and {M}artienssen, {R}. {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{S}elfish genetic elements contribute to hybrid incompatibility and bias or 'drive' their own transmission(1,2). {C}hromosomal drive typically functions in asymmetric female meiosis, whereas gene drive is normally post-meiotic and typically found in males. {H}ere, using single-molecule and single-pollen genome sequencing, we describe {T}eosinte {P}ollen {D}rive, an instance of gene drive in hybrids between maize ({Z}ea mays ssp. mays) and teosinte mexicana ({Z}. mays ssp. mexicana) that depends on {RNA} interference ({RNA}i). 22-nucleotide small {RNA}s from a non-coding {RNA} hairpin in mexicana depend on {D}icer-like 2 ({D}cl2) and target {T}eosinte {D}rive {R}esponder 1 ({T}dr1), which encodes a lipase required for pollen viability. {D}cl2, {T}dr1 and the hairpin are in tight pseudolinkage on chromosome 5, but only when transmitted through the male. {I}ntrogression of mexicana into early cultivated maize is thought to have been critical to its geographical dispersal throughout the {A}mericas(3), and a tightly linked inversion in mexicana spans a major domestication sweep in modern maize(4). {A} survey of maize traditional varieties and sympatric populations of teosinte mexicana reveals correlated patterns of admixture among unlinked genes required for {RNA}i on at least four chromosomes that are also subject to gene drive in pollen from synthetic hybrids. {T}eosinte {P}ollen {D}rive probably had a major role in maize domestication and diversification, and offers an explanation for the widespread abundance of 'self' small {RNA}s in the germ lines of plants and animals.},
  keywords = {},
  booktitle = {},
  journal = {{N}ature},
  volume = {633},
  numero = {8029},
  pages = {380--388 + 19 p.},
  ISSN = {0028-0836},
  year = {2024},
  DOI = {10.1038/s41586-024-07788-0},
  URL = {https://www.documentation.ird.fr/hor/fdi:010092921},
}