Tran H. S. auteur aut IRD Vu D. Q. auteur aut IRD Nguyen D. Q. auteur aut IRD Bui D. T. auteur aut IRD Do T. U. auteur aut IRD Le T. T. H. auteur aut IRD Tran T. T. T. auteur aut IRD Pham H. N. auteur aut IRD Nguyen K. H. auteur aut IRD Du Hoang T. auteur aut IRD Banuls Anne-Laure auteur aut IRD Pulliat G. auteur aut IRD Théry S. auteur aut IRD Bettarel Yvan auteur aut IRD Auguet J. C. auteur aut IRD Nguyen Q. H. auteur aut IRD text journalArticle eng text/pdf born digital access Antimicrobial resistance (AMR) has increased significantly due to the widespread transmission of multidrugresistant (MDR) bacteria and antibiotic-resistance genes (ARGs) within and between animals, environments, and humans. Unfortunately, the AMR situation in the coastal areas is little known. In this study, we investigated the occurrence and distribution of MDR Enterobacteriaceae from water and sediment samples collected in Nha Trang Bay, Viet Nam. Overall, 48/107 (45.8 %) identified and isolated bacteria belong to risk group 2 pathogens. More than 57 % of Enterobacteriaceae isolates exhibited MDR phenotypes, in which Escherichia coli, Klebsiella pneumoniae, and Citrobacter freundii were the most prevalent species. In addition, eight ARGs including sul1, sul2, sul3, tetQ, tetB, mecA, blaVIM and blaKPC were detected with high abundance in most of water and sediment samples. Notably, class 1 integron-integrase gene intI1 was widely distributed (95.8 %) in all samples with a total absolute abundance of 2.9 x 105 copies/ml water and 9.7 x 107 copies/g sediment. We also identified significant relationships between sul3, tetB, blaVIM, blaKPC and intI1 with bacterial density, chlorophyll A, phosphorus and temperature. These observations suggest that intI1 gene and nutrients could promote the emergence and propagation of antibiotic-resistance bacteria (ARB) and ARGs in the Nha Trang Bay. specialized Antibiotic-resistant genes Class 1 integron-integrase gene Enterobacteriaceae Environmental factors Multidrug resistant bacteria Nha Trang Bay East Sea VIET NAM NHA TRANG BAIE EST MER 050 034 038 084 83 104084 [9 p.] 2025 2352-4855 https://www.documentation.ird.fr/hor/fdi:010092836 10.1016/j.rsma.2025.104084 2352-4855 [F B010092836] https://www.documentation.ird.fr/hor/fdi:010092836 https://www.documentation.ird.fr/intranet/publi/2025-04/010092836.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2025-04-02 2025-11-04 fdi:010092836 fre