@article{fdi:010092836,
  title = {{O}ccurrence of multidrug-resistant {E}nterobacteriaceae and antibiotic-resistant genes in the anthropogenic impacted bay of {N}ha {T}rang, {V}iet {N}am},
  author = {{T}ran, {H}. {S}. and {V}u, {D}. {Q}. and {N}guyen, {D}. {Q}. and {B}ui, {D}. {T}. and {D}o, {T}. {U}. and {L}e, {T}. {T}. {H}. and {T}ran, {T}. {T}. {T}. and {P}ham, {H}. {N}. and {N}guyen, {K}. {H}. and {D}u {H}oang, {T}. and {B}anuls, {A}nne-{L}aure and {P}ulliat, {G}. and {T}h{\'e}ry, {S}. and {B}ettarel, {Y}van and {A}uguet, {J}. {C}. and {N}guyen, {Q}. {H}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A}ntimicrobial resistance ({AMR}) has increased significantly due to the widespread transmission of multidrugresistant ({MDR}) bacteria and antibiotic-resistance genes ({ARG}s) within and between animals, environments, and humans. {U}nfortunately, the {AMR} situation in the coastal areas is little known. {I}n this study, we investigated the occurrence and distribution of {MDR} {E}nterobacteriaceae from water and sediment samples collected in {N}ha {T}rang {B}ay, {V}iet {N}am. {O}verall, 48/107 (45.8 %) identified and isolated bacteria belong to risk group 2 pathogens. {M}ore than 57 % of {E}nterobacteriaceae isolates exhibited {MDR} phenotypes, in which {E}scherichia coli, {K}lebsiella pneumoniae, and {C}itrobacter freundii were the most prevalent species. {I}n addition, eight {ARG}s including sul1, sul2, sul3, tet{Q}, tet{B}, mec{A}, bla{VIM} and bla{KPC} were detected with high abundance in most of water and sediment samples. {N}otably, class 1 integron-integrase gene int{I}1 was widely distributed (95.8 %) in all samples with a total absolute abundance of 2.9 x 105 copies/ml water and 9.7 x 107 copies/g sediment. {W}e also identified significant relationships between sul3, tet{B}, bla{VIM}, bla{KPC} and int{I}1 with bacterial density, chlorophyll {A}, phosphorus and temperature. {T}hese observations suggest that int{I}1 gene and nutrients could promote the emergence and propagation of antibiotic-resistance bacteria ({ARB}) and {ARG}s in the {N}ha {T}rang {B}ay.},
  keywords = {{A}ntibiotic-resistant genes ; {C}lass 1 integron-integrase gene ; {E}nterobacteriaceae ; {E}nvironmental factors ; {M}ultidrug resistant bacteria ; {N}ha {T}rang {B}ay ; {E}ast {S}ea ; {VIET} {NAM} ; {NHA} {TRANG} {BAIE} ; {EST} {MER}},
  booktitle = {},
  journal = {{R}egional {S}tudies in {M}arine {S}cience},
  volume = {83},
  numero = {},
  pages = {104084 [9 p.]},
  ISSN = {2352-4855},
  year = {2025},
  DOI = {10.1016/j.rsma.2025.104084},
  URL = {https://www.documentation.ird.fr/hor/fdi:010092836},
}