@article{fdi:010092697,
  title = {{A}frican schistosomes in small mammal communities : perspectives from a spatio-temporal survey in the vicinity of {L}ake {G}uiers, {S}enegal},
  author = {{K}incaid-{S}mith, {J}ulien and {S}avassi, {B}sae and {S}enghor, {B}. and {D}iagne, {C}hristophe {A}midi and {N}iang, {Y}. and {K}ane, {M}. and {T}atard, {C}. and {B}rouat, {C}arine and {G}ranjon, {L}aurent},
  editor = {},
  language = {{ENG}},
  abstract = {{S}chistosomiasis is a neglected tropical disease of public health significance. {I}n view of its elimination as a public health problem by 2030, adopting a {O}ne {H}ealth approach is necessary, considering its multidimensional nature. {A}nimal reservoirs, in particular, pose a significant threat to schistosomiasis control in {A}frica and beyond. {I}n this study, we conducted a spatio-temporal survey of {S}chistosoma infections in small mammal communities and intermediate snail hosts in the vicinity of {L}ake {G}uiers in northern {S}enegal. {S}ampling campaigns were undertaken four times between {A}pril 2021 and {A}ugust 2022 around eight villages. {A} total of 534 small mammals of four species, primarily {H}ubert's multimammate mice {M}astomys huberti, were captured. {O}ut of 498 individuals examined, only 18 rodents (17 {M}. huberti and 1 {A}rvicanthis niloticus) were infected with schistosomes. {T}he infection rates in {M}. huberti varied over time (prevalence range: 2.4% to 9.3%, intensity range: 4 to 132), and space (prevalence range: 3.1% to 40%, intensity range: 2 to 110) and were higher in adult hosts captured during or just after the rainy season, a time when older individuals dominate in rodent populations. {U}sing a multi-locus molecular approach (cox1 and {ITS}) on {S}chistosoma larvae (cercariae and miracidia) and adult worms, we identified {S}chistosoma mansoni as the most widespread species. {W}e also detected {S}chistosoma bovis and {S}chistosoma haematobium in {M}. huberti from one locality ({T}emeye). {A}lthough no {S}chistosoma hybrids were found, the discovery of a male {S}. mansoni and a female {S}. bovis pair raises concerns about potential hybridization patterns that could occur in rodents. {F}inally, three snail species were found infected (25 {B}iomphalaria pfeifferi, 3 {B}ulinus truncatus and 1 {B}ulinus senegalensis) including with {S}. mansoni, {S}. bovis, {S}. haematobium and {S}. haematobium x {S}. bovis hybrids. {O}ur findings highlight the spatial-temporal variations of {S}chistosoma infections in rodents and emphasize the need for fine-scale monitoring over time and space for effective {O}ne {H}ealth measures and ensuring the sustainability of schistosomiasis control efforts.},
  keywords = {{SENEGAL} ; {ZONE} {TROPICALE} ; {GUIERS} {LAC}},
  booktitle = {},
  journal = {{PL}os {N}eglected {T}ropical {D}iseases},
  volume = {18},
  numero = {12},
  pages = {e0012721 [25 p.]},
  ISSN = {1935-2735},
  year = {2024},
  DOI = {10.1371/journal.pntd.0012721},
  URL = {https://www.documentation.ird.fr/hor/fdi:010092697},
}