Ben Salah H. auteur aut IRD Carraz Maëlle auteur aut IRD Kammoun M. auteur aut IRD text journalArticle eng Naturally occurring hydroxamic acid derivatives are biosynthesized by microorganisms (siderophores) and plants (benzoxazinoids). Recent developments in drug related research have highlighted the promising biological and pharmacological properties that the hydroxamic acid function may offer for the enhancement of therapeutic applications. This study reports on the full synthesis of a new dihydroisoquinoline hydroxamic acid (2-Hydroxy-3,3-dimethyl-7-nitro-3,4-dihydroisoquinolin-1(2H)-one). It also describes its cytotoxicity with regard to the human hepatocarcinoma cell line Hep3B. specialized 020PHYCHI 10 4 2648-2653 2014 2321-807X https://www.documentation.ird.fr/hor/fdi:010092393 10.24297/jac.v10i4.5503 2321-807X [F B010092393] https://www.documentation.ird.fr/hor/fdi:010092393 IRD - Base Horizon / Pleins textes 2024-11-28 2024-11-28 fdi:010092393 fre