<?xml version="1.0"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Synthesis and cytotoxic activity of a novel dihydroisoquinoline-derived hydroxamic acid</dc:title>
  <dc:creator>Ben Salah, H.</dc:creator>
  <dc:creator>/Carraz, Ma&#xEB;lle</dc:creator>
  <dc:creator>Kammoun, M.</dc:creator>
  <dc:description>Naturally occurring&#xA0;hydroxamic&#xA0;acid derivatives are biosynthesized by microorganisms (siderophores) and plants (benzoxazinoids). Recent developments in drug related research have highlighted the promising biological and pharmacological properties that the&#xA0;hydroxamic&#xA0;acid function may offer for the enhancement of therapeutic applications. This study reports on the full synthesis of a new dihydroisoquinoline hydroxamic acid (2-Hydroxy-3,3-dimethyl-7-nitro-3,4-dihydroisoquinolin-1(2H)-one). It also describes its cytotoxicity with regard to the human hepatocarcinoma cell line Hep3B.</dc:description>
  <dc:date>2014</dc:date>
  <dc:type>text</dc:type>
  <dc:identifier>https://www.documentation.ird.fr/hor/fdi:010092393</dc:identifier>
  <dc:identifier>fdi:010092393</dc:identifier>
  <dc:identifier>Ben Salah H., Carraz Ma&#xEB;lle, Kammoun M.. Synthesis and cytotoxic activity of a novel dihydroisoquinoline-derived hydroxamic acid. 2014, 10 (4), 2648-2653</dc:identifier>
  <dc:language>EN</dc:language>
</oai_dc:dc>