@article{fdi:010092393, title = {{S}ynthesis and cytotoxic activity of a novel dihydroisoquinoline-derived hydroxamic acid}, author = {{B}en {S}alah, {H}. and {C}arraz, {M}a{\¨e}lle and {K}ammoun, {M}.}, editor = {}, language = {{ENG}}, abstract = {{N}aturally occurring hydroxamic acid derivatives are biosynthesized by microorganisms (siderophores) and plants (benzoxazinoids). {R}ecent developments in drug related research have highlighted the promising biological and pharmacological properties that the hydroxamic acid function may offer for the enhancement of therapeutic applications. {T}his study reports on the full synthesis of a new dihydroisoquinoline hydroxamic acid (2-{H}ydroxy-3,3-dimethyl-7-nitro-3,4-dihydroisoquinolin-1(2{H})-one). {I}t also describes its cytotoxicity with regard to the human hepatocarcinoma cell line {H}ep3{B}.}, keywords = {}, booktitle = {}, journal = {{J}ournal of {A}dvances in {C}hemistry}, volume = {10}, numero = {4}, pages = {2648--2653}, ISSN = {2321-807{X}}, year = {2014}, DOI = {10.24297/jac.v10i4.5503}, URL = {https://www.documentation.ird.fr/hor/fdi:010092393}, }