@article{fdi:010092299, title = {{F}ield evidence for manipulation of mosquito host selection by the human malaria parasite, {P}lasmodium falciparum}, author = {{V}antaux, {A}. and {Y}ao, {F}. and {D}omonbabele, {F}. and {G}uissou, {E}. and {Y}ameogo, {B}.{K}. and {G}ouagna, {L}ouis-{C}l{\'e}ment and {F}ontenille, {D}idier and {R}enaud, {F}. and {S}imard, {F}r{\'e}d{\'e}ric and {C}ostantini, {C}arlo and {T}homas, {F}. and {M}ouline, {K}arine and {R}oche, {B}enjamin and {C}ohuet, {A}nna and {D}abir{\'e}, {K}.{R}. and {L}ef{\`e}vre, {T}.}, editor = {}, language = {{ENG}}, abstract = {{W}hether the malaria parasite {P}lasmodium falciparum can manipulate mosquito host choice in ways that enhance parasite transmission toward humans is unknown. {W}e assessed the influence of {P}. falciparum on the blood-feeding behaviour of three of its major vectors ({A}nopheles coluzzii, {A}n. gambiae and {A}n. arabiensis) in {B}urkina {F}aso. {H}ost preference assays using odour-baited traps revealed no effect of infection on mosquito long-range anthropophily. {H}owever, the identification of the blood meal origin of mosquitoes showed that females carrying sporozoites, the mature transmissible stage of the parasite, displayed a 24% increase in anthropophagy compared to both females harbouring oocysts, the parasite immature stage, and uninfected individuals. {U}sing a mathematical model, we further showed that this increased anthropophagy in infectious females resulted in a 250% increase in parasite transmission potential, everything else being equal. {T}his important epidemiological consequence highlights the importance of vector control tools targeting infectious females.}, keywords = {{BURKINA} {FASO}}, booktitle = {}, journal = {{P}eer {C}ommunity {J}ournal}, volume = {1}, numero = {}, pages = {e13 [37 ]}, ISSN = {2804-3871}, year = {2021}, DOI = {10.24072/pcjournal.13}, URL = {https://www.documentation.ird.fr/hor/fdi:010092299}, }