Horizon 1 1 17 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES Cd4 cell count criteria to determine when to initiate antiretroviral therapy in human immunodeficiency virus-infected children Pediatric Infectious Disease Journal 966-968 HIV CD4 antiretroviral treatment ART initiation WHO children Asia 2010 fdi:010092295 ENG Pediatric Infectious Disease Journal 0891-3668 ISI:000282069700014 10 10.1097/INF.0b013e3181e0554c https://www.documentation.ird.fr/hor/fdi:010092295 https://www.documentation.ird.fr/intranet/publi/2024-12/010092295.pdf 29 Horizon (IRD) We evaluated the validity of CD4 count against CD4% criteria of 2008 World Health Organization guideline for initiating antiretroviral therapy using the data of 446 human immunodeficiency virus-infected Asian children aged 1 to 12 years who were screened to the Pediatric Randomized of Early versus Deferred Initiation in Cambodia and Thailand study. The overall sensitivity and specificity were 34% and 98%, respectively. Using the current CD4 count criteria would globally result in 66% missed opportunity to initiate treatment in a timely fashion. Raising CD4 count thresholds should be considered to increase its sensitivity and reduce missed opportunity. 052 ; 050 UR174 Cambodge / Thaïlande