Cd4 cell count criteria to determine when to initiate antiretroviral therapy in human immunodeficiency virus-infected children Wongsawat, J. Puthanakit, T. Kanjanavanit, S. Hansudewechakul, R. Ngampiyaskul, C. Kerr, S. J. Ubolyam, S. Suwanlerk, T. Kosalaraksa, P. Luesomboon, W. /Ngo-Giang-Huong, Nicole Chandara, M. Saphonn, V. Ruxrungtham, K. Ananworanich, J. HIV CD4 antiretroviral treatment ART initiation WHO children Asia We evaluated the validity of CD4 count against CD4% criteria of 2008 World Health Organization guideline for initiating antiretroviral therapy using the data of 446 human immunodeficiency virus-infected Asian children aged 1 to 12 years who were screened to the Pediatric Randomized of Early versus Deferred Initiation in Cambodia and Thailand study. The overall sensitivity and specificity were 34% and 98%, respectively. Using the current CD4 count criteria would globally result in 66% missed opportunity to initiate treatment in a timely fashion. Raising CD4 count thresholds should be considered to increase its sensitivity and reduce missed opportunity. 2010 text https://www.documentation.ird.fr/hor/fdi:010092295 fdi:010092295 Wongsawat J., Puthanakit T., Kanjanavanit S., Hansudewechakul R., Ngampiyaskul C., Kerr S. J., Ubolyam S., Suwanlerk T., Kosalaraksa P., Luesomboon W., Ngo-Giang-Huong Nicole, Chandara M., Saphonn V., Ruxrungtham K., Ananworanich J.. Cd4 cell count criteria to determine when to initiate antiretroviral therapy in human immunodeficiency virus-infected children. 2010, 29 (10), 966-968 EN