@article{fdi:010092295, title = {{C}d4 cell count criteria to determine when to initiate antiretroviral therapy in human immunodeficiency virus-infected children}, author = {{W}ongsawat, {J}. and {P}uthanakit, {T}. and {K}anjanavanit, {S}. and {H}ansudewechakul, {R}. and {N}gampiyaskul, {C}. and {K}err, {S}. {J}. and {U}bolyam, {S}. and {S}uwanlerk, {T}. and {K}osalaraksa, {P}. and {L}uesomboon, {W}. and {N}go-{G}iang-{H}uong, {N}icole and {C}handara, {M}. and {S}aphonn, {V}. and {R}uxrungtham, {K}. and {A}nanworanich, {J}.}, editor = {}, language = {{ENG}}, abstract = {{W}e evaluated the validity of {CD}4 count against {CD}4% criteria of 2008 {W}orld {H}ealth {O}rganization guideline for initiating antiretroviral therapy using the data of 446 human immunodeficiency virus-infected {A}sian children aged 1 to 12 years who were screened to the {P}ediatric {R}andomized of {E}arly versus {D}eferred {I}nitiation in {C}ambodia and {T}hailand study. {T}he overall sensitivity and specificity were 34% and 98%, respectively. {U}sing the current {CD}4 count criteria would globally result in 66% missed opportunity to initiate treatment in a timely fashion. {R}aising {CD}4 count thresholds should be considered to increase its sensitivity and reduce missed opportunity.}, keywords = {{HIV} ; {CD}4 ; antiretroviral treatment ; {ART} initiation ; {WHO} ; children ; {A}sia}, booktitle = {}, journal = {{P}ediatric {I}nfectious {D}isease {J}ournal}, volume = {29}, numero = {10}, pages = {966--968}, ISSN = {0891-3668}, year = {2010}, DOI = {10.1097/{INF}.0b013e3181e0554c}, URL = {https://www.documentation.ird.fr/hor/fdi:010092295}, }