@article{fdi:010092012,
  title = {{B}ioaccumulation of polycyclic aromatic hydrocarbons and microbiota dynamics across developmental stages of the {A}sian tiger mosquito, {A}edes albopictus exposed to urban pollutants},
  author = {{A}ntonelli, {P}. and {G}rizard, {S}. and {T}ran, {F}. {H}. and {L}ejon, {D}. and {B}ellemain, {A}. and {V}an, and {M}avingui, {P}. and {R}oiz, {D}avid and {S}imard, {F}r{\'e}d{\'e}ric and {M}artin, {E}. and {A}brouk, {D}. and {V}igneron, {A}. and {M}inard, {G}. and {M}oro, {C}. {V}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A}edes albopictus mosquitoes face numerous anthropic stressors in urban areas. {T}hese xenobiotics not only impact mosquito physiology but also shape the composition of their microbiota, which play important roles in host physiological traits. {P}olycyclic aromatic hydrocarbons ({PAH}s) are ubiquitous environmental pollutants known to alter mosquito metabolism, but no studies have yet investigated their impact on microbiota. {U}sing a bespoke indoor mesocosm tailored for {A}e. albopictus mosquitoes, we investigated the dynamics of bacterial communities in both mosquitoes and their larval breeding sites following chronic exposure to a cocktail of {PAH}s consisting of benzo[a]pyrene, benz[a]anthracene, chrysene and benzo[b]fluoranthene. {O}ur findings showed that {PAH}s have a stage-specific effect on mosquito microbiota, with a higher impact in larvae than in adults, contributing to 12.5 % and 4.5 % of the {PAH}s-induced variations, respectively. {T}he presence of {PAH}s in the treated mesocosm led to the enrichment of bacterial families and genera known for their ability to catabolize {PAH}s, such as {C}omamonadaceae and {R}aoultella (increasing from 19 % to 30 % and from 1.2 % to 5.6 %, respectively). {C}onversely, prevalent taxa found in mosquito microbiota like {W}olbachia and {C}edecea exhibited a reduction (decreasing from 4 % to 0.8 % and from 12.8 % to 6.4 %, respectively). {T}his reduction could be attributed to the competitive advantage gained by {PAH}-degrading taxa, or it could reflect a direct sensitivity to {PAH} exposure. {O}verall, this indicates a shift in microbiota composition favoring bacteria that can thrive in a {PAH}-contaminated environment. {PAH}s persisted in the water of breeding sites only the first 45 days of the experiment. {B}enzo[a]pyrene and benzo[b]fluoranthene were more susceptible to bioaccumulation in larval tissues over time. {O}verall, this study enhances our understanding of the impact of pollution on mosquitoes and could facilitate future research on the importance of symbiosis in urban-dwelling insect disease vectors. {G}iven the recent advancements in the generation of axenic (microbe-free) and gnotobiotic (mosquitoes with a defined or specific microbiota) mosquitoes, further studies are needed to explore how changes in microbiota composition could influence mosquito responses to pollution, particularly in relation to host fitness, immunity, and vector competence.},
  keywords = {{P}olycyclic aromatic hydrocarbons ; {M}icrobiota ; {M}osquito ; {A}edes albopictus ; {M}esocosm},
  booktitle = {},
  journal = {{E}cotoxicology and {E}nvironmental {S}afety},
  volume = {286},
  numero = {},
  pages = {117214 [13 p.]},
  ISSN = {0147-6513},
  year = {2024},
  DOI = {10.1016/j.ecoenv.2024.117214},
  URL = {https://www.documentation.ird.fr/hor/fdi:010092012},
}