@article{fdi:010091342,
  title = {{P}rospective acceptability of mass drug administration for malaria in {K}edougou region in {S}enegal : a mixed method study},
  author = {{L}egendre, {E}. and {N}diaye, {A}. and {S}ougou, {N}. {M}. and {G}audart, {J}. and {B}a, {E}. {H}. and {R}idde, {V}al{\'e}ry and {L}andier, {J}ordi},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground{I}n {S}enegalese high-burden regions, the existing package of interventions is insufficient to reach the malaria elimination goal. {A}symptomatic carriers of {P}lasmodium contribute significantly to malaria persistence and are not targeted by current interventions. {T}he systematic treatment of all individuals in a community (mass drug administration, {MDA}) is a relevant intervention to tackle asymptomatic infections. {T}he intervention can only be effective with a high participation of the population and, therefore, depends largely on its acceptability. {T}his study aims to investigate the prospective acceptability of {MDA} in the {K}edougou region to inform its potential use in a future strategy.{M}ethods{F}ollowing a 7-construct theoretical framework, prospective acceptability of {MDA} implemented in the rainy season was studied. {I}n four villages, a sequential mixed design, from qualitative to quantitative, was used. {I}n {N}ovember 2021, interviews with healthcare professionals and focus groups with villagers were conducted. {F}indings from thematic analysis informed the development of a questionnaire administered to individuals aged >= 15 years in {M}arch 2022. {B}ased on the questionnaire, an acceptability score was constructed and associations with socio-demographic factors were investigated using a linear mixed model.{R}esults{T}he 7 interviews, the 12 focus groups, and the questionnaire administered to 289 individuals demonstrated a good acceptability of {MDA}. {T}wo potential barriers were identified: the contradiction of taking a medication without feeling sick and the occurrence of side effects; and four facilitators: the perception of malaria as a burden, a good understanding of {MDA}, a good perceived effectiveness, and the resulting economic benefits. {T}he average acceptability score was 3.5 (range from -7 to + 7). {Y}oung adults aged 15 to 21 had a lower acceptability score compared to the other age groups, indicating an additional barrier to acceptability (beta = -0.78 [-1.67;0.1]).{C}onclusion{MDA} is a priori acceptable to communities of {K}edougou region in {S}enegal. {S}ensitization campaigns co-constructed with the communities, especially targeting young adults, are essential to ensure good acceptability.},
  keywords = {{A}symptomatic malaria ; {M}ass drug administration ; {P}rospective ; acceptability ; {M}ixed method ; {SENEGAL}},
  booktitle = {},
  journal = {{M}alaria {J}ournal},
  volume = {23},
  numero = {1},
  pages = {279 [15 p.]},
  year = {2024},
  DOI = {10.1186/s12936-024-05078-8},
  URL = {https://www.documentation.ird.fr/hor/fdi:010091342},
}