Caudal F. auteur aut IRD Roullier C. auteur aut IRD Rodrigues S. auteur aut IRD Dufour A. auteur aut IRD Artigaud S. auteur aut IRD Le Blay G. auteur aut IRD Bazire A. auteur aut IRD Petek Sylvain auteur aut IRD text journalArticle eng text/pdf reformatted digital access Pathogenic bacteria and their biofilms are involved in many diseases and represent a major public health problem, including the development of antibiotic resistance. These biofilms are known to cause chronic infections for which conventional antibiotic treatments are often ineffective. The search for new molecules and innovative solutions to combat these pathogens and their biofilms has therefore become an urgent need. The use of molecules with anti-biofilm activity would be a potential solution to these problems. The marine world is rich in micro- and macro-organisms capable of producing secondary metabolites with original skeletons. An interest in the chemical strategies used by some of these organisms to regulate and/or protect themselves against pathogenic bacteria and their biofilms could lead to the development of bioinspired, eco-responsible solutions. Through this original review, we listed and sorted the various molecules and extracts from marine organisms that have been described in the literature as having strictly anti-biofilm activity, without bactericidal activity. specialized biofilm marine natural products bacteria anti-biofilm 035 034 050 22 7 313 [22 ] 2024 https://www.documentation.ird.fr/hor/fdi:010091158 10.3390/md22070313 [F B010091158] https://www.documentation.ird.fr/hor/fdi:010091158 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2024-09/010091158.pdf IRD - Base Horizon / Pleins textes 2024-09-27 2025-11-06 fdi:010091158 fre