@article{fdi:010091143, title = {{I}mproving the antinutritional profiles of common beans ({P}haseolus vulgaris {L}.) moderately impacts carotenoid bioaccessibility but not mineral solubility}, author = {{A}lvarado-{R}amos, {K}. and {B}ravo-{N}unez, {A}. and {H}alimi, {C}. and {M}aillot, {M}. and {I}card-{V}erni{\`e}re, {C}hrist{\`e}le and {F}orti, {C}. and {P}reite, {C}. and {F}errari, {L}. and {S}ala, {T}. and {L}osa, {A}. and {C}ominelli, {E}. and {S}parvoli, {F}. and {C}amilli, {E}. and {L}isciani, {S}. and {M}arconi, {S}. and {G}eorg{\'e}, {S}. and {M}ouquet {R}ivier, {C}laire and {K}unert, {K}. and {R}eboul, {E}.}, editor = {}, language = {{ENG}}, abstract = {{C}ommon beans are a common staple food with valuable nutritional qualities, but their high contents in antinutritional factors ({ANF}s) can decrease the bioavailability of (i) fat-soluble micronutrients including carotenoids and (ii) minerals. {O}ur objective was to select {ANF}-poor bean lines that would not interfere with carotenoid and mineral bioavailability. {T}o achieve this objective, seeds of commercial and experimental {P}haseolus vulgaris {L}. bean lines were produced for 2 years and the bean's content in {ANF}s (saponins, phytates, tannins, total polyphenols) was assessed. {W}e then measured carotenoid bioaccessibility and mineral solubility (i.e. the fraction of carotenoid and mineral that transfer into the aqueous phase of the digesta and is therefore absorbable) from prepared beans using in vitro digestion. {A}ll beans contained at least 200 mg/100 g of saponins and 2.44 mg/100 g tannins. {T}he low phytic acid (lpa) lines, lpa1 and lpa1(2) exhibited lower phytate levels (approximate to - 80%, p = 0.007 and p = 0.02) than their control {BAT}-93. {H}owever, this decrease had no significant impact on mineral solubility. {HP}5/1 (lpa + phaseolin and lectin {PHA}-{E} free) bean line, induced an improvement in carotenoid bioaccessibility (i.e., + 38%, p = 0.02, and + 32%, p = 0.005, for phytofluene bioaccessibility in 2021 and 2022, respectively). {W}e conclude that decrease in the phytate bean content should thus likely be associated to decreases in other {ANF}s such as tannins or polyphenols to lead to significant improvement of micronutrient bioaccessibility.}, keywords = {}, booktitle = {}, journal = {{S}cientific {R}eports - {N}ature}, volume = {14}, numero = {1}, pages = {11908 [12 ]}, ISSN = {2045-2322}, year = {2024}, DOI = {10.1038/s41598-024-61475-8}, URL = {https://www.documentation.ird.fr/hor/fdi:010091143}, }