Benzosceptrins A and B with a unique benzocyclobutane skeleton and nagelamide S and T from Pacific sponges

Horizon

ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES

Organic Letters

4874-4877 2009

fdi:010090950

ENG

Organic Letters

1523-7060

ISI:000271097100028

10.1021/ol901946h

https://www.documentation.ird.fr/hor/fdi:010090950

https://www.documentation.ird.fr/intranet/publi/2024-08/010090950.pdf

Horizon (IRD)

Four new dimeric pyrrole-2-aminoimidazole alkaloids have been isolated from the Pacific marine sponges Agelas cf. mauritiana and Phakellia sp. They include the unusual C2 symmetrical benzosceptrins A (4) and B (5), which each possess a unique benzocyclobutane skeleton and nagelamides S (6) and T (7). Their structures and relative configuration were elucidated from spectroscopic data. Plausible biogenetic paths for these compounds are also proposed in this paper. 035 UR152